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2024
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ et al..  2024.  Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.. Cell Chem Biol. 31(4):729-742.e13.
Samuel H, Morillo RCampelo, Kafsack BFC.  2024.  Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria Parasites.. Pathogens. 13(11)
Schwer B, Innokentev A, Sanchez AM, Garg A, Shuman S.  2024.  Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.. mBio. 15(7):e0125224.
Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X.  2024.  Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.. Int J Cancer. 154(4):723-737.
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al..  2024.  Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.
Lee AM, Nathan CF.  2024.  Type I interferon exacerbates Mycobacterium tuberculosis induced human macrophage death.. EMBO Rep. 25(7):3064-3089.
Song M, Huang S, Wu X, Zhao Z, Liu X, Wu C, Wang M, Gao J, Ke Z, Ma X et al..  2024.  UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling.. Redox Biol. 76:103349.
Hahn WO, K Parks R, Shen M, Ozorowski G, Janes H, Ballweber-Fleming L, Davis ASWoodward, Duplessis C, Tomai M, Dey AK et al..  2024.  Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies.. J Exp Med. 221(10)
Syed S, Aloe S, Sutherland JH, Holloman WK, Lue NF.  2024.  Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.. PLoS Genet. 20(12):e1011515.
Bosch B, DeJesus MA, Schnappinger D, Rock JM.  2024.  Weak links: Advancing target-based drug discovery by identifying the most vulnerable targets.. Ann N Y Acad Sci. 1535(1):10-19.
2023
Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y et al..  2023.  Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability.. Blood Adv. 7(15):4049-4063.
Sanchez AM, Schwer B, Jork N, Jessen HJ, Shuman S.  2023.  Activities, substrate specificity, and genetic interactions of fission yeast Siw14, a cysteinyl-phosphatase-type inositol pyrophosphatase.. mBio. 14(5):e0205623.
Garg A, Sanchez AM, Miele M, Schwer B, Shuman S.  2023.  Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.. Nucleic Acids Res. 51(7):3094-3115.
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee W-H, Ward AB, Moore JP, Klasse PJ.  2023.  Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. Retrovirology. 20(1):9.
Wong AI, Beites T, Planck KA, Fieweger RA, Eckartt KA, Li S, Poulton NC, VanderVen BC, Rhee KY, Schnappinger D et al..  2023.  Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis.. Elife. 12
Sutherland JH, Holloman WK.  2023.  Determinants governing BRC function evaluated by mutational analysis of Brh2 in Ustilago maydis.. DNA Repair (Amst). 127:103511.
de Miranda R, Cuthbert BJ, Klevorn T, Chao A, Mendoza J, Arbing M, Sieminski PJ, Papavinasasundaram K, Abdul-Hafiz S, Chan S et al..  2023.  Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.. PLoS Pathog. 19(9):e1011650.
Zhan W, Li D, Subramanyaswamy SBevkal, Liu YJing, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H et al..  2023.  Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.. Cell Chem Biol. 30(5):457-469.e11.
Sanchez AM, Garg A, Schwer B, Shuman S.  2023.  Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination.. RNA. 29(6):808-825.
Garg A, Schwer B, Shuman S.  2023.  Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1.. RNA. 29(11):1738-1753.
Morillo RCampelo, Harris CT, Kennedy K, Henning SR, Kafsack BFc.  2023.  Genome-wide profiling of histone modifications in Plasmodium falciparum using CUT&RUN.. Life Sci Alliance. 6(1)
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al..  2023.  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.. Cell Rep Med. 4(4):101003.
Kengne-Ouafo JA, Bah SY, Kemp A, Stewart L, Amenga-Etego L, Deitsch KW, Rayner JC, Billker O, Binka FN, Sutherland CJ et al..  2023.  The global transcriptome of Plasmodium falciparum mid-stage gametocytes (stages II-IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates.. Microbiol Spectr. 11(5):e0382022.
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JHyun, Antanasijevic A, Rantalainen K, Ketas T et al..  2023.  Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. PLoS Pathog. 19(10):e1011601.