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Found 992 results
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2023
Marreiros IM, Marques S, Parreira A, Mastrodomenico V, Mounce BC, Harris CT, Kafsack BF, Billker O, Zuzarte-Luís V, Mota MM.  2023.  A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency.. Commun Biol. 6(1):205.
Lue NF, Autexier C.  2023.  Orchestrating nucleic acid-protein interactions at chromosome ends: telomerase mechanisms come into focus.. Nat Struct Mol Biol. 30(7):878-890.
Hegde P, Orimoloye MO, Sharma S, Engelhart CA, Schnappinger D, Aldrich CC.  2023.  Polyfluorinated salicylic acid analogs do not interfere with siderophore biosynthesis.. Tuberculosis (Edinb). 140:102346.
Agbemelo-Tsomafo C, Adjei S, Kusi KA, Deitsch KW, Amoah D, Obeng-Kyeremeh R, Sumabe AM, Aniweh Y.  2023.  Prevalence of Leucocytozoon infection in domestic birds in Ghana.. PLoS One. 18(11):e0294066.
Gui W, Giardina SF, Balzarini M, Barany F, Kodadek T.  2023.  Reversible Assembly of Proteolysis Targeting Chimeras.. ACS Chem Biol. 18(7):1582-1593.
Harris CT, Tong X, Campelo R, Marreiros IM, Vanheer LN, Nahiyaan N, Zuzarte-Luís VA, Deitsch KW, Mota MM, Rhee KY et al..  2023.  Sexual differentiation in human malaria parasites is regulated by competition between phospholipid metabolism and histone methylation.. Nat Microbiol. 8(7):1280-1292.
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H.  2023.  Structure of the human UBR5 E3 ubiquitin ligase.. Structure. 31(5):541-552.e4.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Hsu H-C, Li D, Zhan W, Ye J, Liu YJing, Leung A, Qin J, Crespo B, Gamo F-J, Zhang H et al..  2023.  Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.. Nat Commun. 14(1):8302.
Xu Y, Ehrt S, Schnappinger D, Beites T.  2023.  Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation.. mBio. 14(6):e0104523.
2022
Benjamin B, Garg A, Jork N, Jessen HJ, Schwer B, Shuman S.  2022.  Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression.. mBio. 13(3):e0103422.
Gourari I, Gomi R, Young M, Jordan G, Liongson M, Heras A, Gerber LM, Thomas C, Tsirilakis K, Ono J et al..  2022.  Asthma 17q21 polymorphism associates with decreased risk of COVID-19 in children.. Pediatr Pulmonol. 57(11):2855-2860.
Heydarchi B, Fong DS, Gao H, Salazar-Quiroz NA, Edwards JM, Gonelli CA, Grimley S, Aktepe TE, Mackenzie C, Wales WJ et al..  2022.  Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.. Cell Rep Med. 3(5):100635.
Moretti J, Jia B, Hutchins Z, Roy S, Yip H, Wu J, Shan M, Jaffrey SR, Coers J, J Blander M.  2022.  Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.. Nat Immunol. 23(5):705-717.
Koh E-I, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A et al..  2022.  Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.. Proc Natl Acad Sci U S A. 119(15):e2201632119.
Du Y, Kioon MDominique, Laurent P, Chaudhary V, Pierides M, Yang C, Oliver D, Ivashkiv LB, Barrat FJ.  2022.  Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.. J Exp Med. 219(7)
Chaudhary V, Kioon MDominique, Hwang S-M, Mishra B, Lakin K, Kirou KA, Zhang-Sun J, R Wiseman L, Spiera RF, Crow MK et al..  2022.  Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses.. J Exp Med. 219(11)
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M et al..  2022.  CinA mediates multidrug tolerance in Mycobacterium tuberculosis.. Nat Commun. 13(1):2203.
Schwer B, Garg A, Sanchez AM, Bernstein MA, Benjamin B, Shuman S.  2022.  Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast.. mBio. 13(1):e0347621.
Yu EYoung, Cheung N-KV, Lue NF.  2022.  Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cells.. J Hematol Oncol. 15(1):117.
Zhang X, Florini F, Visone JE, Lionardi I, Gross MR, Patel V, Deitsch KW.  2022.  A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites.. Elife. 11
Zhang X, Deitsch KWilliam, Dzikowski R.  2022.  CRISPR-Cas9 Editing of the Plasmodium falciparum Genome: Special Applications.. Methods Mol Biol. 2470:241-253.
Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA et al..  2022.  CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.. Nat Microbiol. 7(6):766-779.
Zhang H, Ginn J, Zhan W, Liu YJ, Leung A, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2022.  Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.. J Med Chem. 65(13):9350-9375.
Garg A, Shuman S, Schwer B.  2022.  Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.. Nucleic Acids Res. 50(2):803-819.