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Anopheles mosquito

Novel Maneuver Helps Malaria Parasite Dodge the Immune System

Researchers at Weill Cornell Medicine have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system, sometimes for years. It turns out that the parasite, Plasmodium falciparum, can shut down a key set of genes, rendering itself “immunologically invisible.”

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chromosomes with telomeres

Study Finds Protein Partnership Protects Chromosomes

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers reveal protein interactions that could explain how the enzyme telomerase is tightly regulated to prevent cells from dividing uncontrollably or aging prematurely. The preclinical study, published April 17 in Nucleic...

Dr. Sabine Ehrt

Dr. Sabine Ehrt Named Chair of the Department of Microbiology and Immunology at Weill Cornell Medicine

(New York, April 14, 2025)—Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine, effective July 1.

The department, which is comprised of microbiologists and immunologists, focuses on the body’s interaction with microbes like...

image of a cough cloud

Study Discovers Tuberculosis Genes Necessary for Airborne Transmission

Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to researchers from Weill Cornell Medicine and the Massachusetts Institute of Technology. The findings provide new targets for tuberculosis therapies that could simultaneously treat infection and prevent the spread of bacteria. 

Until now, very little was known about this transmission process—when...

tuberculosis affects the lungs

Designing Self-Destructing Bacteria to Make Effective Tuberculosis Vaccines

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response. Two preclinical studies, published, Jan. 10 in Nature Microbiology, tackle the challenge of engineering bacteria that are safe for use in controlled human infection trials or as better vaccines. While TB is under control in most developed countries, the...

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