Updates from the Chair | Microbiology and Immunology

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Prestigious MERIT Grant Funds Research on How the Immune System Can Banish HIV

July 17, 2024

Weill Cornell Medicine has received $4.2 million to study how the immune system in some people infected with HIV can keep the virus under control, which could lead to novel therapeutic strategies for thwarting or eliminating HIV. Dr. Brad Jones, associate professor of immunology in medicine in the Division of Infectious Diseases at Weill...

image of Mycobacterium tuberculosis, the bacterium that causes tuberculosis

NIH Funds Consortium to Accelerate Development of New TB Treatments

July 8, 2024

A new consortium co-led by Weill Cornell Medicine, has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis (TB). Investigators at the University of California, San Francisco; Johns Hopkins Medicine; and Vanderbilt University Medical Center comprise the other co-leads.

The Preclinical Design...

New Lab Test to Detect Persistent HIV Strains in Africa May Aid Search for Cure

July 2, 2024

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.

The study, published July 2 in Nature Communications, helps fill a major gap in human immunodeficiency virus (HIV) research. Most HIV studies...

pink macrophages engulfing orange rodlike bacteria

An Immune Powerhouse: Dr. Carl Nathan on the Potential of Interferon-γ

April 22, 2024

Dr. Carl Nathan, chair of the department of microbiology and immunology and the R.A. Rees Pritchett Professor of Microbiology at Weill Cornell Medicine, has co-authored a review in Science on the immune protein interferon-gamma. He answered questions about its history and prospects as a therapeutic.

How was IFN-γ's basic biological role discovered?

In 1969-1971, while I was in medical school, I addressed a...

Structural Study Points the Way to Better Malaria Drugs

January 18, 2024

Structural insights into a potent antimalarial drug candidate’s interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

The antimalarial molecule, TDI-8304, is one of a new class of experimental therapeutics that targets the proteasome, an essential, multiprotein complex in P. falciparum...

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