Carolina Trujillo, Ph.D.
Carolina obtained her Ph.D. in Microbiology from Boston University. In 2009 she joined Dr. Sabine Ehrt’s Lab as a Postdoctoral Associate and has contributed to multiple projects in the lab including efforts to characterize mechanisms important for Mycobacterium tuberculosis virulence, validation of new drug targets for tuberculosis, and identifying molecular processes required for paucibacillary persistence.
Shipra Grover, Ph.D.
I am a new postdoctoral associate who joined Dr. Dirk Schnappinger’s laboratory at Department of Microbiology and Immunology, Weill Cornell in April 2014. Prior to arriving at Cornell, I obtained my PhD in Molecular Microbiology from the University of Birmingham, UK under the supervision of Prof. Gurdyal S. Besra. I am currently working on the TresCantos Open Lab project which is a collaborative effort between Schnappinger Lab at Weill Cornell and Tres Cantos Open Lab foundation, Galaxo Smith Kline, Spain. I am focusing on employing high throughput methods for screening of anti-mycobacterial compounds against the essential genes of mycobacteria and evaluating their potential as drug targets.
S. Grover,L. J. Alderwick, A. K. Mishra, A. Bhatt, G.S. Besra, Benzothiazinones mediate killing of Corynebacterianeae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis. Journal of Biological Chemistry 2014, 289, 6177-6187
Meike Baumgart, Kerstin Luder, Shipra Grover, Cornelia Gätgens , Gurdyal S. Besra, Julia Frunzke, IpsA, a novel LacI-type regulator, is required for inositol-1 derived lipid formation in Corynebacteria and Mycobacteria. BMC Biology 2013, 11:122
S. Grover*, M. Jankute*, A. K. Rana, G. S. Besra, Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets. Future Microbiol 2012 Jan;7(1):129-47.
S. Grover*, M. Jankute*, H. Birch, G.S. Besra, Genetics of Arabinogalactan and Lipoarabinomannan biosynthesis. Molecular Genetics of Mycobacteria Second Ed. ASM Press. (Accepted, in press)
Jeanette Sutherland, Ph.D.
Jeanette Sutherland completed her Ph.D. in Biochemistry and Molecular Biology at New York Medical College. She studied the repair mechanism of stabilized bacterial topoisomerase I cleavage complexes as part of an overall strategy to develop antibacterial drugs targeting topoisomerase I.
She joined the Holloman lab in July of 2011 and is currently working on how homologous recombination functions in DNA repair to maintain genomic stability.
Kojic, M, Sutherland JH, Pérez-Martín J, and Holloman WK. (2013). Initiation of meiotic recombination in Ustilago maydis. Genetics. 195(4):1231-40.
Liu IF, Sutherland JH, Cheng B, and Tse-Dinh, YC. (2011). Topoisomerase I function during E. coli response to antibiotics and stress enhances cell killing from stabilization of its cleavage complex. J. Antimicrob. Chem. 66(7):1518-24.
Sutherland JH and Tse-Dinh YC. (2010). Analysis of RuvABC and RecG involvement in E. coli response to covalent topoisomerase-DNA complex. J Bacteriol. 192(17):4445-4451.
Ruojun Wang, Ph.D.
Ruojun grew up in Shanghai and graduated from Fudan University before moving to NYC for graduate school at Weill Cornell Medicine in 2012. She joined the Ehrt lab in 2013 as a Ph.D. student and is currently a postdoctoral associate. Her research focuses on the microbial and host components that facilitate the persistence of Mycobacterium tuberculosis in the body. Outside of the lab, Ruojun enjoys traveling and taking photos of squirrels in Central Park.