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Found 998 results
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2025
Yang Z, Zhang L, Ottavi S, Geri JB, Perkowski A, Jiang X, Pfau D, Bryk R, Aubé J, Zimmerman M et al..  2025.  ACOD1-mediated lysosomal membrane permeabilization contributes to Mycobacterium tuberculosis-induced macrophage death.. Proc Natl Acad Sci U S A. 122(12):e2425309122.
Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W et al..  2025.  AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.. Sci Adv. 11(34):eadv6937.
Du Y, Faz-Lopez B, Kioon MDominique, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet M-E, Gordon JK et al..  2025.  Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.. J Exp Med. 222(3)
Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al..  2025.  A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.
Mishra S, Singh PRanjan, Hu X, Lopez-Quezada L, Jinich A, Jahn R, Geurts L, Shen N, DeJesus MA, Hartman T et al..  2025.  Candidate transmission survival genome of Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 122(10):e2425981122.
J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.
Ames L, Allen R, Boshoff HIM, Cleghorn LAT, Engelhart CA, Schnappinger D, Parish T.  2025.  Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors.. ACS Infect Dis.
Truong A, Hu R, Quan B, Bailey MA, Schroeder EA, Sylvester K, Neveu G, Kafsack BFC, Fitzgerald MC, Derbyshire ER.  2025.  Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis.. iScience. 28(6):112545.
Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al..  2025.  The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.
Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al..  2025.  Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.
Ohara K, Assaad MAl, McNulty SN, Alnajar H, Sboner A, Wilkes DC, He F, Xiang JZhaoying, Mathew S, Elemento O et al..  2025.  Detection of rare and novel gene fusions in patients with diffuse glioma: An institutional retrospective study.. J Neuropathol Exp Neurol. 84(3):269-271.
Innokentev A, Sanchez AM, Monetti M, Schwer B, Shuman S.  2025.  Efn1 and Efn2 are extracellular 5'-nucleotidases induced during the fission yeast response to phosphate starvation.. mBio. 16(1):e0299224.
Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al..  2025.  Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.
Healy C, Ehrt S, Gouzy A.  2025.  An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH.. mBio. 16(1):e0282524.
Innokentev A, Sanchez AM, Bednor L, Babor J, Schwer B, Shuman S.  2025.  Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery.. RNA.
Dupnik KM, Dorvil N, Ward M, Rivera V, Apollon A, Dumont E, Sued O, Pape JW, Koenig SP.  2025.  Histoplasma capsulatum Not Detected in People with HIV and Systemic Symptoms in Port-au-Prince, Haiti.. AIDS Res Hum Retroviruses.
Klasse PJ, Sanders RW, Ward AB, Wilson IA, Moore JP.  2025.  The HIV-1 envelope glycoprotein: structure, function and interactions with neutralizing antibodies.. Nat Rev Microbiol.
Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al..  2025.  A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.
Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al..  2025.  Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.
Healy C, Ioerger TR, Ehrt S, Gouzy A.  2025.  Identifying genetic determinants of Mycobacterium tuberculosis acid growth arrest by transposon mutagenesis coupled with next-generation sequencing (Tn-seq).. Microbiol Resour Announc. 14(8):e0006025.
Zhou W, Zhou JZ, Ahmed A, Kim MJoon, Guo C-J, Sonnenberg GF.  2025.  ILC3s sense gut microbiota through STING to initiate immune tolerance.. Immunity. 58(7):1762-1777.e7.
Johnson WC, Alivisatos A, Smith TC, Van N, Soni V, Wallach JB, Clark NA, Fitzgerald TA, Whiteley JJ, Tan S et al..  2025.  Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action.. Cell Syst. :101348.
J Blander M.  2025.  Macrophage barrier responses to oncogenic transformation.. Curr Opin Immunol. 92:102524.
Chaudhary V, Mishra B, Kioon MDominique, Du Y, Ivashkiv LB, Crow MK, Barrat FJ.  2025.  Mechanosensing regulates pDC activation in the skin through NRF2 activation.. J Exp Med. 222(3)
Liu Q, Engelhart CA, Wallach JB, Tiwari D, Ge P, Manna A, Panda S, McCue WM, Wong T-Y, Sharma S et al..  2025.  Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial Agents.. J Med Chem. 68(3):3065-3087.