Microbiology and Immunology

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Publications

Found 965 results

Author Title Type [ Year

]

2025

Yang Z, Zhang L, Ottavi S, Geri JB, Perkowski A, Jiang X, Pfau D, Bryk R, Aubé J, Zimmerman M et al.. 2025. ACOD1-mediated lysosomal membrane permeabilization contributes to Mycobacterium tuberculosis-induced macrophage death.. Proc Natl Acad Sci U S A. 122(12):e2425309122.

Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al.. 2025. A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.

Mishra S, Singh PRanjan, Hu X, Lopez-Quezada L, Jinich A, Jahn R, Geurts L, Shen N, DeJesus MA, Hartman T et al.. 2025. Candidate transmission survival genome of Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 122(10):e2425981122.

Ames L, Allen R, Boshoff HIM, Cleghorn LAT, Engelhart CA, Schnappinger D, Parish T. 2025. Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors.. ACS Infect Dis.

Truong A, Hu R, Quan B, Bailey MA, Schroeder EA, Sylvester K, Neveu G, Kafsack BFC, Fitzgerald MC, Derbyshire ER. 2025. Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis.. iScience. 28(6):112545.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al.. 2025. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.

Innokentev A, Sanchez AM, Monetti M, Schwer B, Shuman S. 2025. Efn1 and Efn2 are extracellular 5'-nucleotidases induced during the fission yeast response to phosphate starvation.. mBio. 16(1):e0299224.

Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al.. 2025. Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.

Healy C, Ehrt S, Gouzy A. 2025. An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH.. mBio. 16(1):e0282524.

Klasse PJ, Sanders RW, Ward AB, Wilson IA, Moore JP. 2025. The HIV-1 envelope glycoprotein: structure, function and interactions with neutralizing antibodies.. Nat Rev Microbiol.

Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al.. 2025. Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.

Healy C, Ioerger TR, Ehrt S, Gouzy A. 2025. Identifying genetic determinants of Mycobacterium tuberculosis acid growth arrest by transposon mutagenesis coupled with next-generation sequencing (Tn-seq).. Microbiol Resour Announc. 14(8):e0006025.

Johnson WC, Alivisatos A, Smith TC, Van N, Soni V, Wallach JB, Clark NA, Fitzgerald TA, Whiteley JJ, Tan S et al.. 2025. Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action.. Cell Syst. :101348.

Liu Q, Engelhart CA, Wallach JB, Tiwari D, Ge P, Manna A, Panda S, McCue WM, Wong T-Y, Sharma S et al.. 2025. Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial Agents.. J Med Chem. 68(3):3065-3087.

Zhang M, Allen R, Ames L, Engelhart CA, Quach D, Lv X, Xiao G, Wang H, Wang J, Zhou L et al.. 2025. Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in Mycobacterium tuberculosis.. Antimicrob Agents Chemother. :e0036825.

Jinich A, Zaveri A, DeJesus MA, Spencer A, Almada-Monter R, Flores-Bautista E, Smith CM, Sassetti CM, Rock JM, Ehrt S et al.. 2025. The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality.. Mol Microbiol. 124(1):91-101.

Caniels TG, Prabhakaran M, Ozorowski G, MacPhee KJ, Wu W, van der Straten K, Agrawal S, Derking R, Reiss EIMM, Millard K et al.. 2025. Precise targeting of HIV broadly neutralizing antibody precursors in humans.. Science. 389(6759):eadv5572.

Moore JP. 2025. The RV144 Trial Might Still Yield Useful Information.. Curr HIV Res.

Florini F, Visone JE, Hadjimichael E, Malpotra S, Nötzel C, Kafsack BFC, Deitsch KW. 2025. scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance.. Nat Microbiol. 10(6):1417-1430.

Nilson DJ, Schwer B, Almo SC, Shuman S, Ghosh A. 2025. Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin.. Nucleic Acids Res. 53(14)

Krieger IV, Sukheja P, Yang B, Tang S, Selle D, Woods A, Engelhart C, Kumar P, Harbut MB, Liu D et al.. 2025. SuFEx-based antitubercular compound irreversibly inhibits Pks13.. Nature.

Mostert D, Braun J, Zimmerman MD, Engelhart CA, Berndl S, Quoika PK, Kany AM, Proietto J, Penalva-Lopez S, Wallach JB et al.. 2025. Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly.. Chem Sci. 16(21):9472-9483.

Schwer B, Prucker I, Sanchez AM, Babor J, Jessen HJ, Shuman S. 2025. Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast.. mBio. 16(5):e0038925.

Singh A, Zwerneman LT, Planck K, Kaneko T, Perkowski AJ, Suh CM, Alex A, Bean J, Burns-Huang K, Zhang D et al.. 2025. Thioquinazolinones as Antituberculosis Agents Targeting Phosphopantetheinyl Transferase.. J Med Chem. 68(14):14645-14698.