Submitted by jom4013 on December 3, 2020 - 3:57pm
Title | Sensing danger through a "finger". |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Ma X |
Journal | J Exp Med |
Volume | 215 |
Issue | 12 |
Pagination | 2969-2971 |
Date Published | 2018 12 03 |
ISSN | 1540-9538 |
Keywords | Interleukin-12, Protein Transport, Signal Transduction, Transcription Factors, Transcription, Genetic |
Abstract | In this issue of , the study by Chen et al. (https://doi.org/10.1084/jem.20181031) reveals a previously unrecognized role of cellular nucleic acid-binding protein (Cnbp) as a novel transcriptional regulator of interleukin-12β (IL-12β) transcription and IL-12-driven, Th1-mediated immune responses, which has important implications for both host defense and inflammatory disease. |
DOI | 10.1084/jem.20182034 |
Alternate Journal | J Exp Med |
PubMed ID | 30459157 |
PubMed Central ID | PMC6279409 |