Submitted by jom4013 on December 3, 2020 - 3:57pm
| Title | Sensing danger through a "finger". |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Ma X |
| Journal | J Exp Med |
| Volume | 215 |
| Issue | 12 |
| Pagination | 2969-2971 |
| Date Published | 2018 12 03 |
| ISSN | 1540-9538 |
| Keywords | Interleukin-12, Protein Transport, Signal Transduction, Transcription Factors, Transcription, Genetic |
| Abstract | In this issue of , the study by Chen et al. (https://doi.org/10.1084/jem.20181031) reveals a previously unrecognized role of cellular nucleic acid-binding protein (Cnbp) as a novel transcriptional regulator of interleukin-12β (IL-12β) transcription and IL-12-driven, Th1-mediated immune responses, which has important implications for both host defense and inflammatory disease. |
| DOI | 10.1084/jem.20182034 |
| Alternate Journal | J Exp Med |
| PubMed ID | 30459157 |
| PubMed Central ID | PMC6279409 |
