Microbiology and Immunology

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2024

Abramson J, Dobeš J, Lyu M, Sonnenberg GF. 2024. The emerging family of RORγt+ antigen-presenting cells.. Nat Rev Immunol. 24(1):64-77.

Garg A, Sanchez AM, Schwer B, Shuman S. 2024. Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation.. J Biol Chem. 300(3):105718.

Klasse PJ. 2024. Fusion peptide-directed antibodies: Humoral armor against HIV-1 infection.. Sci Transl Med. 16(730):eadl2162.

Bednor L, Sanchez AM, Garg A, Shuman S, Schwer B. 2024. Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IP6 kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast.. mBio. 15(2):e0306223.

Caniels TG, Medina-Ramírez M, Zhang S, Kratochvil S, Xian Y, Koo J-H, Derking R, Samsel J, van Schooten J, Pecetta S et al.. 2024. Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.. Sci Immunol. 9(98):eadk9550.

Horn V, Sonnenberg GF. 2024. Group 3 innate lymphoid cells in intestinal health and disease.. Nat Rev Gastroenterol Hepatol. 21(6):428-443.

Alwine J, Goodrum F, Banfield B, Bloom D, Britt WJ, Broadbent AJ, Campos SK, Casadevall A, Chan GC, Cliffe AR et al.. 2024. The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence.. J Virol. 98(9):e0124024.

Ghosh S, Wimberly-Gard G, Jacewicz A, Schwer B, Shuman S. 2024. Identification, characterization, and structure of a tRNA splicing enzyme RNA 5'-OH kinase from the pathogenic fungi Mucorales.. RNA. 30(12):1674-1685.

Nelson AN, Shen X, Vekatayogi S, Zhang S, Ozorowski G, Dennis M, Sewall LM, Milligan E, Davis D, Cross KA et al.. 2024. Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.. Sci Immunol. 9(98):eadm7097.

Krieger IV, Yalamanchili S, Dickson P, Engelhart CA, Zimmerman MD, Wood J, Clary E, Nguyen J, Thornton N, Centrella PA et al.. 2024. Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.. ACS Infect Dis. 10(5):1561-1575.

Casanova J-L, MacMicking JD, Nathan CF. 2024. Interferon-γ and infectious diseases: Lessons and prospects.. Science. 384(6693):eadl2016.

Miller AH, Marks F, Chan L, Botella H, Schnappinger D, Ehrt S. 2024. Interruption of mycothiol synthesis and intracellular redox status impact iron-regulated reporter activation in Mycobacterium smegmatis.. Microbiol Spectr. 12(7):e0048724.

Qu D, Ge P, Botella L, Park SWoong, Lee H-N, Thornton N, Bean JM, Krieger IV, Sacchettini JC, Ehrt S et al.. 2024. Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin.. Nat Commun. 15(1):4161.

Lee AM, Laurent P, Nathan CF, Barrat FJ. 2024. Neutrophil-plasmacytoid dendritic cell interaction leads to production of type I IFN in response to Mycobacterium tuberculosis.. Eur J Immunol. 54(3):e2350666.

Chen L, Xu G, Song X, Zhang L, Chen C, Xiang G, Wang S, Zhang Z, Wu F, Yang X et al.. 2024. A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.. Cancer Lett. 583:216635.

Juste MAntoine Je, Joseph Y, Lespinasse D, Apollon A, Jamshidi P, Lee MHee, Ward M, Brill E, Duffus Y, Chukwukere U et al.. 2024. People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis.. Pathog Immun. 9(2):172-193.

Hviid L, Jensen AR, Deitsch KW. 2024. PfEMP1 and var genes - Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity.. Adv Parasitol. 125:53-103.

Dupnik K, Rivera VR, Dorvil N, Duffus Y, Akbarnejad H, Gao Y, Liu J, Apollon A, Dumont E, Riviere C et al.. 2024. Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification Among Patients With Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-income Countries.. Open Forum Infect Dis. 11(7):ofae356.

Sanders RW, Moore JP. 2024. Progress on priming HIV-1 immunity.. Science. 384(6697):738-739.

Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al.. 2024. Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.

Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ et al.. 2024. Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.. Cell Chem Biol. 31(4):729-742.e13.

Samuel H, Morillo RCampelo, Kafsack BFC. 2024. Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria Parasites.. Pathogens. 13(11)

Schwer B, Innokentev A, Sanchez AM, Garg A, Shuman S. 2024. Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.. mBio. 15(7):e0125224.

Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X. 2024. Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.. Int J Cancer. 154(4):723-737.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.