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Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
N
Gandotra S
,
Jang S
,
Murray PJ
,
Salgame P
,
Ehrt S
. 2007.
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.
.
Infect Immun. 75(11):5127-34.
Ma X
,
Gri G
,
Trinchieri G
. 1996.
A novel ets-2-related nuclear factor is involved in transcriptional activation of the human interleukin-12 p40 gene promoter in response to interferon-gamma and LPS stimulation of monocytic cells.
.
Ann N Y Acad Sci. 795:357-60.
Gold B
,
Smith R
,
Nguyen Q
,
Roberts J
,
Ling Y
,
Quezada LLopez
,
Somersan S
,
Warrier T
,
Little D
,
Pingle M
et al.
. 2016.
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
.
J Med Chem. 59(13):6027-44.
Ehrt S
,
Shiloh MU
,
Ruan J
,
Choi M
,
Gunzburg S
,
Nathan C
,
Xie Q
,
Riley LW
. 1997.
A novel antioxidant gene from Mycobacterium tuberculosis.
.
J Exp Med. 186(11):1885-96.
Forbes CJ
,
Lowry D
,
Geer L
,
Veazey RS
,
Shattock RJ
,
Klasse PJohan
,
Mitchnick M
,
Goldman L
,
Doyle LA
,
Muldoon BCO
et al.
. 2011.
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
.
J Control Release. 156(2):161-9.
Forbes CJ
,
Lowry D
,
Geer L
,
Veazey RS
,
Shattock RJ
,
Klasse PJohan
,
Mitchnick M
,
Goldman L
,
Doyle LA
,
Muldoon BCO
et al.
. 2011.
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
.
J Control Release. 156(2):161-9.
Werts C
,
le Bourhis L
,
Liu J
,
Magalhaes JG
,
Carneiro LA
,
Fritz JH
,
Stockinger S
,
Balloy V
,
Chignard M
,
Decker T
et al.
. 2007.
Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.
.
Eur J Immunol. 37(9):2499-508.
Warrier T
,
Kapilashrami K
,
Argyrou A
,
Ioerger TR
,
Little D
,
Murphy KC
,
Nandakumar M
,
Park S
,
Gold B
,
Mi J
et al.
. 2016.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 113(31):E4523-30.
Lin G
,
Chidawanyika T
,
Tsu C
,
Warrier T
,
Vaubourgeix J
,
Blackburn C
,
Gigstad K
,
Sintchak M
,
Dick L
,
Nathan C
. 2013.
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
.
J Am Chem Soc. 135(27):9968-71.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
M
Shi S
,
Nathan C
,
Schnappinger D
,
Drenkow J
,
Fuortes M
,
Block E
,
Ding A
,
Gingeras TR
,
Schoolnik G
,
Akira S
et al.
. 2003.
MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.
.
J Exp Med. 198(7):987-97.
Williams KJ
,
Boshoff HI
,
Krishnan N
,
Gonzales J
,
Schnappinger D
,
Robertson BD
. 2011.
The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo.
.
Tuberculosis (Edinb). 91(6):549-55.
Buter J
,
Cheng T-Y
,
Ghanem M
,
Grootemaat AE
,
Raman S
,
Feng X
,
Plantijn AR
,
Ennis T
,
Wang J
,
Cotton RN
et al.
. 2019.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
.
Nat Chem Biol. 15(9):889-899.
Buter J
,
Cheng T-Y
,
Ghanem M
,
Grootemaat AE
,
Raman S
,
Feng X
,
Plantijn AR
,
Ennis T
,
Wang J
,
Cotton RN
et al.
. 2019.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
.
Nat Chem Biol. 15(9):889-899.
Gandotra S
,
Lebron MB
,
Ehrt S
. 2010.
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.
.
PLoS Pathog. 6(8):e1001040.
Botella H
,
Vaubourgeix J
,
Lee MHee
,
Song N
,
Xu W
,
Makinoshima H
,
Glickman MS
,
Ehrt S
. 2017.
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.
.
EMBO J. 36(4):536-548.
Gouzy A
,
Larrouy-Maumus G
,
Bottai D
,
Levillain F
,
Dumas A
,
Wallach JB
,
Caire-Brandli I
,
de Chastellier C
,
Di Wu T-
,
Poincloux R
et al.
. 2014.
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.
.
PLoS Pathog. 10(2):e1003928.
Gouzy A
,
Larrouy-Maumus G
,
Bottai D
,
Levillain F
,
Dumas A
,
Wallach JB
,
Caire-Brandli I
,
de Chastellier C
,
Di Wu T-
,
Poincloux R
et al.
. 2014.
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.
.
PLoS Pathog. 10(2):e1003928.
Stephanou NC
,
Gao F
,
Bongiorno P
,
Ehrt S
,
Schnappinger D
,
Shuman S
,
Glickman MS
. 2007.
Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.
.
J Bacteriol. 189(14):5237-46.
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