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Found 80 results
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2026
Visone JE, Florini F, Hadjimichael E, Patel V, Deitsch KW.  2026.  Mechanistic insights into coordinated var transcriptional switching in malaria parasites.. EMBO J. 45(8):2614-2637.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T.  2026.  Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.. Commun Biol.
2025
J Blander M.  2025.  Macrophage barrier responses to oncogenic transformation.. Curr Opin Immunol. 92:102524.
Chaudhary V, Mishra B, Kioon MDominique, Du Y, Ivashkiv LB, Crow MK, Barrat FJ.  2025.  Mechanosensing regulates pDC activation in the skin through NRF2 activation.. J Exp Med. 222(3)
Liu Q, Engelhart CA, Wallach JB, Tiwari D, Ge P, Manna A, Panda S, McCue WM, Wong T-Y, Sharma S et al..  2025.  Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial Agents.. J Med Chem. 68(3):3065-3087.
Zhang M, Allen R, Ames L, Engelhart CA, Quach D, Lv X, Xiao G, Wang H, Wang J, Zhou L et al..  2025.  Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in Mycobacterium tuberculosis.. Antimicrob Agents Chemother. :e0036825.
Iliev ID, J Blander M, Collins N, Guo C-J, Longman RS, Sonnenberg GF, Zeng MY, Artis D.  2025.  Microbiota-mediated mechanisms of mucosal immunity across the lifespan.. Nat Immunol.
Jinich A, Zaveri A, DeJesus MA, Spencer A, Almada-Monter R, Flores-Bautista E, Smith CM, Sassetti CM, Rock JM, Ehrt S et al..  2025.  The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality.. Mol Microbiol. 124(1):91-101.
2024
Qu D, Ge P, Botella L, Park SWoong, Lee H-N, Thornton N, Bean JM, Krieger IV, Sacchettini JC, Ehrt S et al..  2024.  Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin.. Nat Commun. 15(1):4161.
2023
Sharma R, Hartman TE, Beites T, Kim J-H, Eoh H, Engelhart CA, Zhu L, Wilson DJ, Aldrich CC, Ehrt S et al..  2023.  Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis.. mBio. 14(4):e0034023.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Bacolod MD, Fisher PB, Barany F.  2023.  Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines.. Adv Cancer Res. 158:233-292.
Nathan C.  2023.  Mycobacterium tuberculosis as teacher.. Nat Microbiol. 8(9):1606-1608.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al..  2023.  Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. ACS Med Chem Lett. 14(7):970-976.
2022
Zhang X, Deitsch KW.  2022.  The mystery of persistent, asymptomatic Plasmodium falciparum infections.. Curr Opin Microbiol. 70:102231.
2021
Zhang H, Hsu H-C, Kahne SC, Hara R, Zhan W, Jiang X, Burns-Huang K, Ouellette T, Imaeda T, Okamoto R et al..  2021.  Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.. J Med Chem. 64(9):6262-6272.
Black KA, Duan L, Mandyoli L, Selbach BP, Xu W, Ehrt S, Sacchettini JC, Rhee KY.  2021.  Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis.. J Exp Med. 218(7)
Bacolod MD, Barany F.  2021.  MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types.. Curr Cancer Drug Targets. 21(4):360-374.
Schrader SM, Botella H, Jansen R, Ehrt S, Rhee K, Nathan C, Vaubourgeix J.  2021.  Multiform antimicrobial resistance from a metabolic mutation.. Sci Adv. 7(35)
Beites T, Jansen RS, Wang R, Jinich A, Rhee KY, Schnappinger D, Ehrt S.  2021.  Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.. Nat Commun. 12(1):6593.
Gold B, Warrier T, Nathan C.  2021.  A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis.. Methods Mol Biol. 2314:611-635.
2020
Neveu G, Beri D, Kafsack BFc.  2020.  Metabolic regulation of sexual commitment in Plasmodium falciparum.. Curr Opin Microbiol. 58:93-98.
2019
Buter J, Cheng T-Y, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN et al..  2019.  Mycobacterium tuberculosis releases an antacid that remodels phagosomes.. Nat Chem Biol. 15(9):889-899.
2018
Hsu M, Lue NF.  2018.  The mechanisms of K. lactis Cdc13 in telomere DNA-binding and telomerase regulation.. DNA Repair (Amst). 61:37-45.
Ehrt S, Schnappinger D, Rhee KY.  2018.  Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis.. Nat Rev Microbiol. 16(8):496-507.