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Publications

Found 51 results
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2020
Zaveri A, Wang R, Botella L, Sharma R, Zhu L, Wallach JB, Song N, Jansen RS, Rhee KY, Ehrt S et al..  2020.  Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.. Mol Microbiol.
Matthews KA, Senagbe KM, Nötzel C, Gonzales CA, Tong X, Rijo-Ferreira F, Bhanu NV, Miguel-Blanco C, Lafuente-Monasterio MJose, Garcia BA et al..  2020.  Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases.. ACS Infect Dis. 6(5):1058-1075.
2019
Wu J, Mu R, Sun M, Zhao N, Pan M, Li H, Dong Y, Sun Z, Bai J, Hu M et al..  2019.  Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .. ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K et al..  2019.  Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .. ACS Infect Dis. 5(8):1433-1445.
2018
McAulay K, Saito K, Warrier T, Walsh KFrances, Mathurin LDaniel, Royal-Mardi G, Lee MHee, Ocheretina O, Pape JWilliam, Fitzgerald DW et al..  2018.  Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.. mBio. 9(6)
Shastry S, Steinberg-Neifach O, Lue N, Stone MD.  2018.  Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain.. Nucleic Acids Res. 46(6):3088-3102.
Oh S, Park Y, Engelhart CA, Wallach JB, Schnappinger D, Arora K, Manikkam M, Gac B, Wang H, Murgolo N et al..  2018.  Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.. J Med Chem. 61(22):9952-9965.
2017
Botella L, Vaubourgeix J, Livny J, Schnappinger D.  2017.  Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.. Nat Commun. 8:14731.
Botella H, Yang G, Ouerfelli O, Ehrt S, Nathan CF, Vaubourgeix J.  2017.  Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.. mBio. 8(5)
Zhou Q, Holloman WK.  2017.  Dss1 Regulates Association of Brh2 with Rad51.. Biochemistry. 56(26):3318-3327.
2015
Iliev ID.  2015.  Dectin-1 Exerts Dual Control in the Gut.. Cell Host Microbe. 18(2):139-41.
Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J.  2015.  The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. Nat Immunol. 16(6):599-608.
Goodsmith N, Guo XV, Vandal OH, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P et al..  2015.  Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.. PLoS Pathog. 11(2):e1004645.
2014
Sander AF, Lavstsen T, Rask TS, Lisby M, Salanti A, Fordyce SL, Jespersen JS, Carter R, Deitsch K, Theander TG et al..  2014.  DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.. Nucleic Acids Res. 42(4):2270-81.
Zhou Q, Holloman WK.  2014.  Dual DNA-binding domains shape the interaction of Brh2 with DNA.. DNA Repair (Amst). 22:104-11.
2013
Lew JM, Mao C, Shukla M, Warren A, Will R, Kuznetsov D, Xenarios I, Robertson BD, Gordon SV, Schnappinger D et al..  2013.  Database resources for the tuberculosis community.. Tuberculosis (Edinb). 93(1):12-7.
Heinberg A, Siu E, Stern C, Lawrence EA, Ferdig MT, Deitsch K, Kirkman L.  2013.  Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.. Mol Microbiol. 88(4):702-12.
Lue NF, Chan J.  2013.  Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida species.. J Biol Chem. 288(40):29115-23.
2012
Spadoni I, Iliev ID, Rossi G, Rescigno M.  2012.  Dendritic cells produce TSLP that limits the differentiation of Th17 cells, fosters Treg development, and protects against colitis.. Mucosal Immunol. 5(2):184-93.
Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H et al..  2012.  Detection and treatment of subclinical tuberculosis.. Tuberculosis (Edinb). 92(6):447-52.
Zhou Q, Kojic M, Holloman WK.  2012.  Dss1 release activates DNA binding potential in Brh2.. Biochemistry. 51(45):9137-46.
2011
Wei J-R, Krishnamoorthy V, Murphy K, Kim J-H, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ.  2011.  Depletion of antibiotic targets has widely varying effects on growth.. Proc Natl Acad Sci U S A. 108(10):4176-81.
de Sena-Tomás C, Fernández-Álvarez A, Holloman WK, Pérez-Martín J.  2011.  The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus Ustilago maydis in planta.. Plant Cell. 23(4):1654-65.