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Found 98 results
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2026
Seshadri C, Flynn JAL, Maiello P, Schnappinger D, Wilkinson RJ, Gordon SB, Mwandumba HC, Jambo KC, Hoft DF, Rubin EJ et al..  2026.  Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trials.. Lancet Microbe. :101278.
2025
Mishra S, Singh PRanjan, Hu X, Lopez-Quezada L, Jinich A, Jahn R, Geurts L, Shen N, DeJesus MA, Hartman T et al..  2025.  Candidate transmission survival genome of Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 122(10):e2425981122.
J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.
Ames L, Allen R, Boshoff HIM, Cleghorn LAT, Engelhart CA, Schnappinger D, Parish T.  2025.  Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors.. ACS Infect Dis.
Truong A, Hu R, Quan B, Bailey MA, Schroeder EA, Sylvester K, Neveu G, Kafsack BFC, Fitzgerald MC, Derbyshire ER.  2025.  Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis.. iScience. 28(6):112545.
Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al..  2025.  The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.
2024
Ghosh S, Dantuluri S, Jacewicz A, Sanchez AM, Abdullahu L, Damha MJ, Schwer B, Shuman S.  2024.  Characterization of tRNA splicing enzymes RNA ligase and tRNA 2'-phosphotransferase from the pathogenic fungi Mucorales.. RNA. 30(4):367-380.
Giardina SF, Valdambrini E, Singh PK, Bacolod MD, Babu-Karunakaran G, Peel M, J Warren D, Barany F.  2024.  Combinatorial Ubiquitination REal-time PROteolysis (CURE-PROs): A Modular Platform for Generating Reversible, Self-Assembling Bifunctional Targeted Degraders.. J Med Chem. 67(7):5473-5501.
Grigsby SJ, Prasad GVRKrishn, Wallach JB, Mittal E, Hsu F-F, Schnappinger D, Philips JA.  2024.  CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis.. Cell Rep. 43(1):113607.
Ahmed A, Joseph AM, Zhou J, Horn V, Uddin J, Lyu M, Goc J, Sockolow RE, Wing JB, Vivier E et al..  2024.  CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation.. Nature. 630(8018):976-983.
2023
Garg A, Sanchez AM, Miele M, Schwer B, Shuman S.  2023.  Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.. Nucleic Acids Res. 51(7):3094-3115.
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee W-H, Ward AB, Moore JP, Klasse PJ.  2023.  Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. Retrovirology. 20(1):9.
Wong AI, Beites T, Planck KA, Fieweger RA, Eckartt KA, Li S, Poulton NC, VanderVen BC, Rhee KY, Schnappinger D et al..  2023.  Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis.. Elife. 12
2022
Moretti J, Jia B, Hutchins Z, Roy S, Yip H, Wu J, Shan M, Jaffrey SR, Coers J, J Blander M.  2022.  Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.. Nat Immunol. 23(5):705-717.
Koh E-I, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A et al..  2022.  Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.. Proc Natl Acad Sci U S A. 119(15):e2201632119.
Du Y, Kioon MDominique, Laurent P, Chaudhary V, Pierides M, Yang C, Oliver D, Ivashkiv LB, Barrat FJ.  2022.  Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.. J Exp Med. 219(7)
Chaudhary V, Kioon MDominique, Hwang S-M, Mishra B, Lakin K, Kirou KA, Zhang-Sun J, R Wiseman L, Spiera RF, Crow MK et al..  2022.  Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses.. J Exp Med. 219(11)
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M et al..  2022.  CinA mediates multidrug tolerance in Mycobacterium tuberculosis.. Nat Commun. 13(1):2203.
Schwer B, Garg A, Sanchez AM, Bernstein MA, Benjamin B, Shuman S.  2022.  Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast.. mBio. 13(1):e0347621.
Yu EYoung, Cheung N-KV, Lue NF.  2022.  Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cells.. J Hematol Oncol. 15(1):117.
Zhang X, Florini F, Visone JE, Lionardi I, Gross MR, Patel V, Deitsch KW.  2022.  A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites.. Elife. 11
Zhang X, Deitsch KWilliam, Dzikowski R.  2022.  CRISPR-Cas9 Editing of the Plasmodium falciparum Genome: Special Applications.. Methods Mol Biol. 2470:241-253.
Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA et al..  2022.  CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.. Nat Microbiol. 7(6):766-779.
2021
Zhao N, Dong W, Kim H, Moallemian R, Lv J, Wang H, Zheng H, Wei F, Ma X.  2021.  Capping protein regulator and myosin 1 linker 3 regulates transcription of key cytokines in activated phagocytic cells.. Cell Signal. 78:109848.
Zainabadi K, Walsh KFrances, Vilbrun SCharles, Mathurin LDaniel, Lee MHee, Saito K, Mishra S, Ocheretina O, Pape JWilliam, Nathan C et al..  2021.  Characterization of Differentially Detectable Mycobacterium tuberculosis in the Sputum of Subjects with Drug-Sensitive or Drug-Resistant Tuberculosis before and after Two Months of Therapy.. Antimicrob Agents Chemother. 65(8):e0060821.