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Found 49 results
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2025
Innokentev A, Sanchez AM, Bednor L, Babor J, Schwer B, Shuman S.  2025.  Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery.. RNA.
2024
Bednor L, Sanchez AM, Garg A, Shuman S, Schwer B.  2024.  Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IP6 kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast.. mBio. 15(2):e0306223.
Caniels TG, Medina-Ramírez M, Zhang S, Kratochvil S, Xian Y, Koo J-H, Derking R, Samsel J, van Schooten J, Pecetta S et al..  2024.  Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.. Sci Immunol. 9(98):eadk9550.
Horn V, Sonnenberg GF.  2024.  Group 3 innate lymphoid cells in intestinal health and disease.. Nat Rev Gastroenterol Hepatol. 21(6):428-443.
2023
Morillo RCampelo, Harris CT, Kennedy K, Henning SR, Kafsack BFc.  2023.  Genome-wide profiling of histone modifications in Plasmodium falciparum using CUT&RUN.. Life Sci Alliance. 6(1)
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al..  2023.  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.. Cell Rep Med. 4(4):101003.
Kengne-Ouafo JA, Bah SY, Kemp A, Stewart L, Amenga-Etego L, Deitsch KW, Rayner JC, Billker O, Binka FN, Sutherland CJ et al..  2023.  The global transcriptome of Plasmodium falciparum mid-stage gametocytes (stages II-IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates.. Microbiol Spectr. 11(5):e0382022.
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JHyun, Antanasijevic A, Rantalainen K, Ketas T et al..  2023.  Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. PLoS Pathog. 19(10):e1011601.
2022
Garg A, Shuman S, Schwer B.  2022.  Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.. Nucleic Acids Res. 50(2):803-819.
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ et al..  2022.  The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization.. J Virol. 96(1):e0155221.
2021
Wipperman MF, Bhattarai SK, Vorkas CKyriakos, Maringati VSuhas, Taur Y, Mathurin L, McAulay K, Vilbrun SCharles, Francois D, Bean J et al..  2021.  Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.. Nat Commun. 12(1):1141.
Su H, Lin K, Tiwari D, Healy C, Trujillo C, Liu Y, Ioerger TR, Schnappinger D, Ehrt S.  2021.  Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity.. J Exp Med. 218(9)
Schwer B, Garg A, Jacewicz A, Shuman S.  2021.  Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.. Proc Natl Acad Sci U S A. 118(33)
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB et al..  2021.  Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.. Cell. 184(17):4579-4592.e24.
Gouzy A, Healy C, Black KA, Rhee KY, Ehrt S.  2021.  Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.. Proc Natl Acad Sci U S A. 118(32)
2020
Sanchez AM, Garg A, Shuman S, Schwer B.  2020.  Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72.. Nucleic Acids Res. 48(9):4811-4826.
Garg A, Shuman S, Schwer B.  2020.  A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination.. Nucleic Acids Res.
2019
Wang C, Li Y, Chu C-M, Zhang X-M, Ma J, Huang H, Wang Y-N, Hong T-Y, Zhang J, Pan X-W et al..  2019.  Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.. EBioMedicine. 39:255-264.
McLean KJarrod, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT et al..  2019.  Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.. Sci Rep. 9(1):13131.
Shan J, Chouchane A, Mokrab Y, Saad M, Boujassoum S, Sayaman RW, Ziv E, Bouaouina N, Remadi Y, Gabbouj S et al..  2019.  Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications.. Front Oncol. 9:1328.
2018
Zhang W, Kim H, Lv J, Zhao N, Ma X.  2018.  Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization.. J Immunol. 200(4):1480-1488.
2017
Murray HW, Luster AD, Zheng H, Ma X.  2017.  Gamma Interferon-Regulated Chemokines in Leishmania donovani Infection in the Liver.. Infect Immun. 85(1)
Puckett S, Trujillo C, Wang Z, Eoh H, Ioerger TR, Krieger I, Sacchettini J, Schnappinger D, Rhee KY, Ehrt S.  2017.  Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 114(11):E2225-E2232.
2015
Schnappinger D.  2015.  Genetic Approaches to Facilitate Antibacterial Drug Development.. Cold Spring Harb Perspect Med. 5(7):a021139.
Murray HW, Mitchell-Flack M, Zheng H, Ma X.  2015.  Granzyme-mediated regulation of host defense in the liver in experimental Leishmania donovani infection.. Infect Immun. 83(2):702-12.