Microbiology and Immunology

You are here

Home > Publications > Publications

Publications

Found 85 results
Author Title [ Type(Desc)] Year
Filters: Author is Ehrt, Sabine  [Clear All Filters]
Journal Article
Vandal OH, Nathan CF, Ehrt S.  2009.  Acid resistance in Mycobacterium tuberculosis.. J Bacteriol. 191(15):4714-21.
Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S.  2009.  Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.. J Bacteriol. 191(2):625-31.
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Boshoff HIM, Xu X, Tahlan K, Dowd CS, Pethe K, Camacho LR, Park T-H, Yun C-S, Schnappinger D, Ehrt S et al..  2008.  Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.. J Biol Chem. 283(28):19329-41.
Schnappinger D, Ehrt S.  2016.  A broader spectrum of tuberculosis.. Nat Med. 22(10):1076-1077.
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Xu W, DeJesus MA, Rücker N, Engelhart CA, Wright MG, Healy C, Lin K, Wang R, Park SWoong, Ioerger TR et al..  2017.  Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.. Antimicrob Agents Chemother. 61(12)
Schnappinger D, O'Brien KM, Ehrt S.  2015.  Construction of conditional knockdown mutants in mycobacteria.. Methods Mol Biol. 1285:151-75.
Ehrt S, Schnappinger D.  2006.  Controlling gene expression in mycobacteria.. Future Microbiol. 1(2):177-84.
Ehrt S, Guo XV, Hickey CM, Ryou M, Monteleone M, Riley LW, Schnappinger D.  2005.  Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor.. Nucleic Acids Res. 33(2):e21.
Vandal OH, Gelb MH, Ehrt S, Nathan CF.  2006.  Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.. Infect Immun. 74(3):1751-6.
Zaveri A, Wang R, Botella L, Sharma R, Zhu L, Wallach JB, Song N, Jansen RS, Rhee KY, Ehrt S et al..  2020.  Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.. Mol Microbiol.
Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H et al..  2012.  Detection and treatment of subclinical tuberculosis.. Tuberculosis (Edinb). 92(6):447-52.
Shi S, Ehrt S.  2006.  Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.. Infect Immun. 74(1):56-63.
Goodsmith N, Guo XV, Vandal OH, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P et al..  2015.  Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.. PLoS Pathog. 11(2):e1004645.
Botella H, Yang G, Ouerfelli O, Ehrt S, Nathan CF, Vaubourgeix J.  2017.  Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.. mBio. 8(5)
Park SWoong, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC et al..  2011.  Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.. PLoS Pathog. 7(9):e1002264.
Shi S, Blumenthal A, Hickey CM, Gandotra S, Levy D, Ehrt S.  2005.  Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.. J Immunol. 175(5):3318-28.
Schnappinger D, Schoolnik GK, Ehrt S.  2006.  Expression profiling of host pathogen interactions: how Mycobacterium tuberculosis and the macrophage adapt to one another.. Microbes Infect. 8(4):1132-40.
Ruecker N, Jansen R, Trujillo C, Puckett S, Jayachandran P, Piroli GG, Frizzell N, Molina H, Rhee KY, Ehrt S.  2017.  Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.. Cell Chem Biol. 24(3):306-315.
Kim J-H, O'Brien KM, Sharma R, Boshoff HIM, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC et al..  2013.  A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.. Proc Natl Acad Sci U S A. 110(47):19095-100.
Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S.  2010.  Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.. Proc Natl Acad Sci U S A. 107(21):9819-24.
Marrero J, Trujillo C, Rhee KY, Ehrt S.  2013.  Glucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice.. PLoS Pathog. 9(1):e1003116.
Hisert KB, MacCoss M, Shiloh MU, K Darwin H, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S et al..  2005.  A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.. Mol Microbiol. 56(5):1234-45.
Santangelo Mde la Paz, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R et al..  2011.  Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.. J Biol Chem. 286(46):40219-31.