Submitted by alp2017 on November 19, 2014 - 11:00am
| Title | Detection and treatment of subclinical tuberculosis. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H, Flynn JA, Hafner R, Handley G, Hanekom W, van Helden P, Kaplan G, Kaufmann SHE, Kim P, Lienhardt C, Mizrahi V, Rubin E, Schnappinger D, Sherman D, Thole J, Vandal O, Walzl G, Warner D, Wilkinson R, Young D |
| Journal | Tuberculosis (Edinb) |
| Volume | 92 |
| Issue | 6 |
| Pagination | 447-52 |
| Date Published | 2012 Nov |
| ISSN | 1873-281X |
| Keywords | Antitubercular Agents, Bacterial Load, Biomarkers, Drug Design, Female, Humans, Immunization Programs, Latent Tuberculosis, Male, Models, Animal, Mycobacterium tuberculosis, South Africa, Tuberculosis, Tuberculosis Vaccines |
| Abstract | Reduction of active disease by preventive therapy has the potential to make an important contribution towards the goal of tuberculosis (TB) elimination. This report summarises discussions amongst a Working Group convened to consider areas of research that will be important in optimising the design and delivery of preventative therapies. The Working Group met in Cape Town on 26th February 2012, following presentation of results from the GC11 Grand Challenges in Global Health project to discover drugs for latent TB. |
| DOI | 10.1016/j.tube.2012.06.004 |
| Alternate Journal | Tuberculosis (Edinb) |
| PubMed ID | 22819716 |
| Grant List | MC_U117588499 / / Medical Research Council / United Kingdom MR/J006874/1 / / Medical Research Council / United Kingdom 077381 / / Wellcome Trust / United Kingdom |