Microbiology and Immunology

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2012
Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H et al..  2012.  Detection and treatment of subclinical tuberculosis.. Tuberculosis (Edinb). 92(6):447-52.
Ginsberg M, James D, Ding B-S, Nolan D, Geng F, Butler JM, Schachterle W, Pulijaal VR, Mathew S, Chasen ST et al..  2012.  Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression.. Cell. 151(3):559-75.
Blumenthal A, Nagalingam G, Huch JH, Walker L, Guillemin GJ, Smythe GA, Ehrt S, Britton WJ, Saunders BM.  2012.  M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.. PLoS One. 7(5):e37314.
Sanyal S, Egée S, Bouyer G, Perrot S, Safeukui I, Bischoff E, Buffet P, Deitsch KW, Mercereau-Puijalon O, David PH et al..  2012.  Plasmodium falciparum STEVOR proteins impact erythrocyte mechanical properties.. Blood. 119(2):e1-8.
Melchers M, Bontjer I, Tong T, P Y Chung N, Klasse PJohan, Eggink D, Montefiori DC, Gentile M, Cerutti A, Olson WC et al..  2012.  Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.. J Virol. 86(5):2488-500.
2011
Sonnenberg GF, Monticelli LA, M Elloso M, Fouser LA, Artis D.  2011.  CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.. Immunity. 34(1):122-34.
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Park SWoong, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC et al..  2011.  Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.. PLoS Pathog. 7(9):e1002264.
Park SWoong, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC et al..  2011.  Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.. PLoS Pathog. 7(9):e1002264.
Santangelo Mde la Paz, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R et al..  2011.  Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.. J Biol Chem. 286(46):40219-31.
Darby CM, Venugopal A, Ehrt S, Nathan CF.  2011.  Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice.. Tuberculosis (Edinb). 91(5):343-7.
Koo M-S, Manca C, Yang G, O'Brien P, Sung N, Tsenova L, Subbian S, Fallows D, Muller G, Ehrt S et al..  2011.  Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.. PLoS One. 6(2):e17091.
Melchers M, Matthews K, de Vries RP, Eggink D, van Montfort T, Bontjer I, van de Sandt C, David K, Berkhout B, Moore JP et al..  2011.  A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells.. Retrovirology. 8:48.
Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C.  2011.  Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.. Cell Host Microbe. 9(1):21-31.
2010
Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S.  2010.  Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.. Proc Natl Acad Sci U S A. 107(21):9819-24.
Seimon TA, Kim M-J, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker L-G, Kaplan G, Nathan C, Tabas I et al..  2010.  Induction of ER stress in macrophages of tuberculosis granulomas.. PLoS One. 5(9):e12772.
Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K et al..  2010.  Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.. Virology. 401(2):236-47.
de Carvalho LPedro S, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY.  2010.  Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.. Chem Biol. 17(10):1122-31.
Rajadhyaksha AM, Elemento O, Puffenberger EG, Schierberl KC, Xiang JZ, Putorti ML, Berciano J, Poulin C, Brais B, Michaelides M et al..  2010.  Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.. Am J Hum Genet. 87(5):643-54.
Gandotra S, Lebron MB, Ehrt S.  2010.  The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.. PLoS Pathog. 6(8):e1001040.
Tan MPing, Sequeira P, Lin WWei, Phong WYee, Cliff P, Ng SHwee, Lee BHeng, Camacho L, Schnappinger D, Ehrt S et al..  2010.  Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses.. PLoS One. 5(10):e13356.
Blumenthal A, Trujillo C, Ehrt S, Schnappinger D.  2010.  Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo.. PLoS One. 5(12):e15667.
Bontjer I, Melchers M, Eggink D, David K, Moore JP, Berkhout B, Sanders RW.  2010.  Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.. J Biol Chem. 285(47):36456-70.
Biswas T, Small J, Vandal O, Odaira T, Deng H, Ehrt S, Tsodikov OV.  2010.  Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.. Structure. 18(10):1353-63.
2009
Vandal OH, Nathan CF, Ehrt S.  2009.  Acid resistance in Mycobacterium tuberculosis.. J Bacteriol. 191(15):4714-21.