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Ehrt, Sabine
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Wang R
,
Kreutzfeldt K
,
Botella H
,
Vaubourgeix J
,
Schnappinger D
,
Ehrt S
. 2019.
Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division.
.
Elife. 8
Healy C
,
Gouzy A
,
Ehrt S
. 2020.
Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host.
.
mBio. 11(2)
O
Danilchanka O
,
Sun J
,
Pavlenok M
,
Maueröder C
,
Speer A
,
Siroy A
,
Marrero J
,
Trujillo C
,
Mayhew DL
,
Doornbos KS
et al.
. 2014.
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.
.
Proc Natl Acad Sci U S A. 111(18):6750-5.
N
Gandotra S
,
Jang S
,
Murray PJ
,
Salgame P
,
Ehrt S
. 2007.
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.
.
Infect Immun. 75(11):5127-34.
Tan MPing
,
Sequeira P
,
Lin WWei
,
Phong WYee
,
Cliff P
,
Ng SHwee
,
Lee BHeng
,
Camacho L
,
Schnappinger D
,
Ehrt S
et al.
. 2010.
Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses.
.
PLoS One. 5(10):e13356.
M
Shi S
,
Nathan C
,
Schnappinger D
,
Drenkow J
,
Fuortes M
,
Block E
,
Ding A
,
Gingeras TR
,
Schoolnik G
,
Akira S
et al.
. 2003.
MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.
.
J Exp Med. 198(7):987-97.
Ehrt S
,
Schnappinger D
. 2007.
Mycobacterium tuberculosis virulence: lipids inside and out.
.
Nat Med. 13(3):284-5.
Lin K
,
O'Brien KM
,
Trujillo C
,
Wang R
,
Wallach JB
,
Schnappinger D
,
Ehrt S
. 2016.
Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense.
.
PLoS Pathog. 12(6):e1005675.
Buter J
,
Cheng T-Y
,
Ghanem M
,
Grootemaat AE
,
Raman S
,
Feng X
,
Plantijn AR
,
Ennis T
,
Wang J
,
Cotton RN
et al.
. 2019.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
.
Nat Chem Biol. 15(9):889-899.
Gandotra S
,
Lebron MB
,
Ehrt S
. 2010.
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.
.
PLoS Pathog. 6(8):e1001040.
Botella H
,
Vaubourgeix J
,
Lee MHee
,
Song N
,
Xu W
,
Makinoshima H
,
Glickman MS
,
Ehrt S
. 2017.
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.
.
EMBO J. 36(4):536-548.
Ehrt S
,
Rhee K
. 2013.
Mycobacterium tuberculosis metabolism and host interaction: mysteries and paradoxes.
.
Curr Top Microbiol Immunol. 374:163-88.
Darby CM
,
Venugopal A
,
Ehrt S
,
Nathan CF
. 2011.
Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice.
.
Tuberculosis (Edinb). 91(5):343-7.
Sakamoto K
,
Kim MJeong
,
Rhoades ER
,
Allavena RE
,
Ehrt S
,
Wainwright HC
,
Russell DG
,
Rohde KH
. 2013.
Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases.
.
Infect Immun. 81(3):764-76.
Ehrt S
,
Schnappinger D
. 2009.
Mycobacterial survival strategies in the phagosome: defence against host stresses.
.
Cell Microbiol. 11(8):1170-8.
Stephanou NC
,
Gao F
,
Bongiorno P
,
Ehrt S
,
Schnappinger D
,
Shuman S
,
Glickman MS
. 2007.
Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.
.
J Bacteriol. 189(14):5237-46.
Ehrt S
,
Rhee K
,
Schnappinger D
. 2015.
Mycobacterial genes essential for the pathogen's survival in the host.
.
Immunol Rev. 264(1):319-26.
de Carvalho LPedro S
,
Fischer SM
,
Marrero J
,
Nathan C
,
Ehrt S
,
Rhee KY
. 2010.
Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.
.
Chem Biol. 17(10):1122-31.
Ehrt S
,
Schnappinger D
,
Rhee KY
. 2018.
Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis.
.
Nat Rev Microbiol. 16(8):496-507.
Vandal OH
,
Pierini LM
,
Schnappinger D
,
Nathan CF
,
Ehrt S
. 2008.
A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.
.
Nat Med. 14(8):849-54.
Blumenthal A
,
Nagalingam G
,
Huch JH
,
Walker L
,
Guillemin GJ
,
Smythe GA
,
Ehrt S
,
Britton WJ
,
Saunders BM
. 2012.
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.
.
PLoS One. 7(5):e37314.
L
Gaur RL
,
Ren K
,
Blumenthal A
,
Bhamidi S
,
González-Nilo FD
,
Gibbs S
,
Jackson M
,
Zare RN
,
Ehrt S
,
Ernst JD
et al.
. 2014.
LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(9):e1004376.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
I
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by boiling lysis.
.
Methods Mol Biol. 235:79-82.
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by alkaline lysis.
.
Methods Mol Biol. 235:75-8.
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