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Publications

Found 74 results
Author Title Type [ Year(Asc)]
Filters: Author is Schnappinger, Dirk  [Clear All Filters]
2011
Duckworth BP, Geders TW, Tiwari D, Boshoff HI, Sibbald PA, Barry CE, Schnappinger D, Finzel BC, Aldrich CC.  2011.  Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis.. Chem Biol. 18(11):1432-41.
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Wei J-R, Krishnamoorthy V, Murphy K, Kim J-H, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ.  2011.  Depletion of antibiotic targets has widely varying effects on growth.. Proc Natl Acad Sci U S A. 108(10):4176-81.
Park SWoong, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC et al..  2011.  Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.. PLoS Pathog. 7(9):e1002264.
Santangelo Mde la Paz, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R et al..  2011.  Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.. J Biol Chem. 286(46):40219-31.
Shi C, Geders TW, Park SWoong, Wilson DJ, Boshoff HI, Abayomi O, Barry CE, Schnappinger D, Finzel BC, Aldrich CC.  2011.  Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.. J Am Chem Soc. 133(45):18194-201.
Williams KJ, Boshoff HI, Krishnan N, Gonzales J, Schnappinger D, Robertson BD.  2011.  The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo.. Tuberculosis (Edinb). 91(6):549-55.
Kim J-H, Wei J-R, Wallach JB, Robbins RS, Rubin EJ, Schnappinger D.  2011.  Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.. Nucleic Acids Res. 39(6):2210-20.
Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C.  2011.  Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.. Cell Host Microbe. 9(1):21-31.