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Publications

Found 20 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Anti-Bacterial Agents  [Clear All Filters]
2019
Zimmerman M, McDonald SL, Ho-Liang H-P, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS et al..  2019.  Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.. J Antibiot (Tokyo). 72(6):469-475.
Subramaniyam S, DeJesus MA, Zaveri A, Smith CM, Baker RE, Ehrt S, Schnappinger D, Sassetti CM, Ioerger TR.  2019.  Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.. BMC Bioinformatics. 20(1):603.
Lee JJin, Lee S-K, Song N, Nathan TO, Swarts BM, Eum S-Y, Ehrt S, Cho S-N, Eoh H.  2019.  Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.. Nat Commun. 10(1):2928.
2017
Liu F, Dawadi S, Maize KM, Dai R, Park SWoong, Schnappinger D, Finzel BC, Aldrich CC.  2017.  Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem. 60(13):5507-5520.
2015
Nathan C.  2015.  Cooperative development of antimicrobials: looking back to look ahead.. Nat Rev Microbiol. 13(10):651-7.
Dai R, Geders TW, Liu F, Park SWoong, Schnappinger D, Aldrich CC, Finzel BC.  2015.  Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.. J Med Chem. 58(13):5208-17.
Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O et al..  2015.  Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.. Cell Host Microbe. 17(2):178-90.
2012
Abt MC, Osborne LC, Monticelli LA, Doering TA, Alenghat T, Sonnenberg GF, Paley MA, Antenus M, Williams KL, Erikson J et al..  2012.  Commensal bacteria calibrate the activation threshold of innate antiviral immunity.. Immunity. 37(1):158-70.
Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS et al..  2012.  Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation.. Nat Med. 18(4):538-46.
Nathan C.  2012.  Fresh approaches to anti-infective therapies.. Sci Transl Med. 4(140):140sr2.
2011
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Wei J-R, Krishnamoorthy V, Murphy K, Kim J-H, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ.  2011.  Depletion of antibiotic targets has widely varying effects on growth.. Proc Natl Acad Sci U S A. 108(10):4176-81.
2009
Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S.  2009.  Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.. J Bacteriol. 191(2):625-31.
2007
Schnappinger D.  2007.  Genomics of host-pathogen interactions.. Prog Drug Res. 64:311,313-43.
2005
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Hisert KB, MacCoss M, Shiloh MU, K Darwin H, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S et al..  2005.  A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.. Mol Microbiol. 56(5):1234-45.
2004
Nathan C.  2004.  Antibiotics at the crossroads.. Nature. 431(7011):899-902.
2000
Kojic M, Holloman WK.  2000.  Shuttle vectors for genetic manipulations in Ustilago maydis.. Can J Microbiol. 46(4):333-8.
1997
Berens C, Schnappinger D, Hillen W.  1997.  The role of the variable region in Tet repressor for inducibility by tetracycline.. J Biol Chem. 272(11):6936-42.
1981
Rowe TC, Rusche JR, Brougham MJ, Holloman WK.  1981.  Purification and properties of a topoisomerase from Ustilago maydis.. J Biol Chem. 256(20):10354-61.