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Found 85 results
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2010
Gandotra S, Lebron MB, Ehrt S.  2010.  The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.. PLoS Pathog. 6(8):e1001040.
Tan MPing, Sequeira P, Lin WWei, Phong WYee, Cliff P, Ng SHwee, Lee BHeng, Camacho L, Schnappinger D, Ehrt S et al..  2010.  Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses.. PLoS One. 5(10):e13356.
Blumenthal A, Trujillo C, Ehrt S, Schnappinger D.  2010.  Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo.. PLoS One. 5(12):e15667.
Biswas T, Small J, Vandal O, Odaira T, Deng H, Ehrt S, Tsodikov OV.  2010.  Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.. Structure. 18(10):1353-63.
2009
Vandal OH, Nathan CF, Ehrt S.  2009.  Acid resistance in Mycobacterium tuberculosis.. J Bacteriol. 191(15):4714-21.
Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S.  2009.  Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.. J Bacteriol. 191(2):625-31.
Klotzsche M, Ehrt S, Schnappinger D.  2009.  Improved tetracycline repressors for gene silencing in mycobacteria.. Nucleic Acids Res. 37(6):1778-88.
Ehrt S, Schnappinger D.  2009.  Mycobacterial survival strategies in the phagosome: defence against host stresses.. Cell Microbiol. 11(8):1170-8.
Blumenthal A, Kobayashi T, Pierini LM, Banaei N, Ernst JD, Miyake K, Ehrt S.  2009.  RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins.. Cell Host Microbe. 5(1):35-46.
Barry CE, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn JA, Schnappinger D, Wilkinson RJ, Young D.  2009.  The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.. Nat Rev Microbiol. 7(12):845-55.
2008
Boshoff HIM, Xu X, Tahlan K, Dowd CS, Pethe K, Camacho LR, Park T-H, Yun C-S, Schnappinger D, Ehrt S et al..  2008.  Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.. J Biol Chem. 283(28):19329-41.
Vandal OH, Pierini LM, Schnappinger D, Nathan CF, Ehrt S.  2008.  A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.. Nat Med. 14(8):849-54.
Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S et al..  2008.  Selective killing of nonreplicating mycobacteria.. Cell Host Microbe. 3(3):137-45.
2007
Gandotra S, Schnappinger D, Monteleone M, Hillen W, Ehrt S.  2007.  In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.. Nat Med. 13(12):1515-20.
Stephanou NC, Gao F, Bongiorno P, Ehrt S, Schnappinger D, Shuman S, Glickman MS.  2007.  Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.. J Bacteriol. 189(14):5237-46.
Ehrt S, Schnappinger D.  2007.  Mycobacterium tuberculosis virulence: lipids inside and out.. Nat Med. 13(3):284-5.
Gandotra S, Jang S, Murray PJ, Salgame P, Ehrt S.  2007.  Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.. Infect Immun. 75(11):5127-34.
Guo XV, Monteleone M, Klotzsche M, Kamionka A, Hillen W, Braunstein M, Ehrt S, Schnappinger D.  2007.  Silencing Mycobacterium smegmatis by using tetracycline repressors.. J Bacteriol. 189(13):4614-23.
2006
Ehrt S, Schnappinger D.  2006.  Controlling gene expression in mycobacteria.. Future Microbiol. 1(2):177-84.
Vandal OH, Gelb MH, Ehrt S, Nathan CF.  2006.  Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.. Infect Immun. 74(3):1751-6.
Shi S, Ehrt S.  2006.  Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.. Infect Immun. 74(1):56-63.
Schnappinger D, Schoolnik GK, Ehrt S.  2006.  Expression profiling of host pathogen interactions: how Mycobacterium tuberculosis and the macrophage adapt to one another.. Microbes Infect. 8(4):1132-40.
Schnappinger D, Ehrt S.  2006.  Introduction: genomic approaches in infectious diseases.. Microbes Infect. 8(6):1611-2.
2005
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Ehrt S, Guo XV, Hickey CM, Ryou M, Monteleone M, Riley LW, Schnappinger D.  2005.  Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor.. Nucleic Acids Res. 33(2):e21.