Submitted by ljc4002 on August 21, 2025 - 2:50pm
| Title | Identifying genetic determinants of Mycobacterium tuberculosis acid growth arrest by transposon mutagenesis coupled with next-generation sequencing (Tn-seq). |
| Publication Type | Journal Article |
| Year of Publication | 2025 |
| Authors | Healy C, Ioerger TR, Ehrt S, Gouzy A |
| Journal | Microbiol Resour Announc |
| Volume | 14 |
| Issue | 8 |
| Pagination | e0006025 |
| Date Published | 2025 Aug 14 |
| ISSN | 2576-098X |
| Abstract | Mycobacterium tuberculosis, the causative agent of tuberculosis, remains the leading global infectious disease killer. Adaptation of Mycobacterium tuberculosis to acidic niches within the host during infection is vital to establish the disease. Here, we present a high-density transposon mutant sequencing library data set identifying genetic determinants of acid growth arrest to serve as a resource. |
| DOI | 10.1128/mra.00060-25 |
| Alternate Journal | Microbiol Resour Announc |
| PubMed ID | 40643003 |
| PubMed Central ID | PMC12352093 |
| Grant List | R21 AI168673-01A1 / / National Institute of Allergy and Infectious Diseases / 22/PATH-S/10678 / SFI_ / Science Foundation Ireland / Ireland P01 AI143575 / AI / NIAID NIH HHS / United States R21 AI168673 / AI / NIAID NIH HHS / United States P01AI143575 / / National Institute of Allergy and Infectious Diseases / |