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Found 985 results
Author Title Type [ Year(Asc)]
2024
Ghosh S, Wimberly-Gard G, Jacewicz A, Schwer B, Shuman S.  2024.  Identification, characterization, and structure of a tRNA splicing enzyme RNA 5'-OH kinase from the pathogenic fungi Mucorales.. RNA. 30(12):1674-1685.
Nelson AN, Shen X, Vekatayogi S, Zhang S, Ozorowski G, Dennis M, Sewall LM, Milligan E, Davis D, Cross KA et al..  2024.  Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.. Sci Immunol. 9(98):eadm7097.
Krieger IV, Yalamanchili S, Dickson P, Engelhart CA, Zimmerman MD, Wood J, Clary E, Nguyen J, Thornton N, Centrella PA et al..  2024.  Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.. ACS Infect Dis. 10(5):1561-1575.
Casanova J-L, MacMicking JD, Nathan CF.  2024.  Interferon-γ and infectious diseases: Lessons and prospects.. Science. 384(6693):eadl2016.
Miller AH, Marks F, Chan L, Botella H, Schnappinger D, Ehrt S.  2024.  Interruption of mycothiol synthesis and intracellular redox status impact iron-regulated reporter activation in Mycobacterium smegmatis.. Microbiol Spectr. 12(7):e0048724.
Qu D, Ge P, Botella L, Park SWoong, Lee H-N, Thornton N, Bean JM, Krieger IV, Sacchettini JC, Ehrt S et al..  2024.  Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin.. Nat Commun. 15(1):4161.
Lee AM, Laurent P, Nathan CF, Barrat FJ.  2024.  Neutrophil-plasmacytoid dendritic cell interaction leads to production of type I IFN in response to Mycobacterium tuberculosis.. Eur J Immunol. 54(3):e2350666.
Chen L, Xu G, Song X, Zhang L, Chen C, Xiang G, Wang S, Zhang Z, Wu F, Yang X et al..  2024.  A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.. Cancer Lett. 583:216635.
Hviid L, Jensen AR, Deitsch KW.  2024.  PfEMP1 and var genes - Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity.. Adv Parasitol. 125:53-103.
Sanders RW, Moore JP.  2024.  Progress on priming HIV-1 immunity.. Science. 384(6697):738-739.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ et al..  2024.  Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.. Cell Chem Biol. 31(4):729-742.e13.
Samuel H, Morillo RCampelo, Kafsack BFC.  2024.  Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria Parasites.. Pathogens. 13(11)
Schwer B, Innokentev A, Sanchez AM, Garg A, Shuman S.  2024.  Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.. mBio. 15(7):e0125224.
Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X.  2024.  Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.. Int J Cancer. 154(4):723-737.
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al..  2024.  Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.
Lee AM, Nathan CF.  2024.  Type I interferon exacerbates Mycobacterium tuberculosis induced human macrophage death.. EMBO Rep. 25(7):3064-3089.
Song M, Huang S, Wu X, Zhao Z, Liu X, Wu C, Wang M, Gao J, Ke Z, Ma X et al..  2024.  UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling.. Redox Biol. 76:103349.
Hahn WO, K Parks R, Shen M, Ozorowski G, Janes H, Ballweber-Fleming L, Davis ASWoodward, Duplessis C, Tomai M, Dey AK et al..  2024.  Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies.. J Exp Med. 221(10)
Syed S, Aloe S, Sutherland JH, Holloman WK, Lue NF.  2024.  Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.. PLoS Genet. 20(12):e1011515.
Bosch B, DeJesus MA, Schnappinger D, Rock JM.  2024.  Weak links: Advancing target-based drug discovery by identifying the most vulnerable targets.. Ann N Y Acad Sci. 1535(1):10-19.
2023
Zi Z, Du S, Zhang L, Wang Y, Ding L, Zhang C, Wang H, Pawlicki J, Cai Y, Yao Y et al..  2023.  Aberrant expression of GOLM1 protects ALK+ anaplastic large cell lymphoma from apoptosis by enhancing BCL-XL stability.. Blood Adv. 7(15):4049-4063.
Sanchez AM, Schwer B, Jork N, Jessen HJ, Shuman S.  2023.  Activities, substrate specificity, and genetic interactions of fission yeast Siw14, a cysteinyl-phosphatase-type inositol pyrophosphatase.. mBio. 14(5):e0205623.
Garg A, Sanchez AM, Miele M, Schwer B, Shuman S.  2023.  Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.. Nucleic Acids Res. 51(7):3094-3115.
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee W-H, Ward AB, Moore JP, Klasse PJ.  2023.  Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. Retrovirology. 20(1):9.