Microbiology and Immunology

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Found 966 results
Author Title Type [ Year(Asc)]
2021
Su H, Lin K, Tiwari D, Healy C, Trujillo C, Liu Y, Ioerger TR, Schnappinger D, Ehrt S.  2021.  Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity.. J Exp Med. 218(9)
Schwer B, Garg A, Jacewicz A, Shuman S.  2021.  Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.. Proc Natl Acad Sci U S A. 118(33)
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB et al..  2021.  Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.. Cell. 184(17):4579-4592.e24.
Gouzy A, Healy C, Black KA, Rhee KY, Ehrt S.  2021.  Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.. Proc Natl Acad Sci U S A. 118(32)
Dingens AS, Pratap P, Malone K, Hilton SK, Ketas T, Cottrell CA, Overbaugh J, Moore JP, Klasse PJ, Ward AB et al..  2021.  High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.. Elife. 10
Brouwer PJM, Antanasijevic A, de Gast M, Allen JD, Bijl TPL, Yasmeen A, Ravichandran R, Burger JA, Ozorowski G, Torres JL et al..  2021.  Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.. NPJ Vaccines. 6(1):24.
Klasse PJ, Nixon DF, Moore JP.  2021.  Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans.. Sci Adv. 7(12)
Dutta E, DeJesus MA, Ruecker N, Zaveri A, Koh E-I, Sassetti CM, Schnappinger D, Ioerger TR.  2021.  An improved statistical method to identify chemical-genetic interactions by exploiting concentration-dependence.. PLoS One. 16(10):e0257911.
Zhang H, Hsu H-C, Kahne SC, Hara R, Zhan W, Jiang X, Burns-Huang K, Ouellette T, Imaeda T, Okamoto R et al..  2021.  Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.. J Med Chem. 64(9):6262-6272.
Black KA, Duan L, Mandyoli L, Selbach BP, Xu W, Ehrt S, Sacchettini JC, Rhee KY.  2021.  Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis.. J Exp Med. 218(7)
Bacolod MD, Barany F.  2021.  MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types.. Curr Cancer Drug Targets. 21(4):360-374.
Schrader SM, Botella H, Jansen R, Ehrt S, Rhee K, Nathan C, Vaubourgeix J.  2021.  Multiform antimicrobial resistance from a metabolic mutation.. Sci Adv. 7(35)
Beites T, Jansen RS, Wang R, Jinich A, Rhee KY, Schnappinger D, Ehrt S.  2021.  Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.. Nat Commun. 12(1):6593.
Gold B, Warrier T, Nathan C.  2021.  A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis.. Methods Mol Biol. 2314:611-635.
Kioon MDominique, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ.  2021.  Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.. J Immunol. 206(7):1631-1641.
Harnagel A, Quezada LLopez, Park SWoong, Baranowski C, Kieser K, Jiang X, Roberts J, Vaubourgeix J, Yang A, Nelson B et al..  2021.  Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress.. Mol Microbiol. 115(2):272-289.
Saito K, Mishra S, Warrier T, Cicchetti N, Mi J, Weber E, Jiang X, Roberts J, Gouzy A, Kaplan E et al..  2021.  Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected.. Sci Transl Med. 13(621):eabg2612.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.
Racine-Brzostek SE, Yang HS, Jack GA, Chen Z, Chadburn A, Ketas TJ, Francomano E, Klasse PJ, Moore JP, McDonough KA et al..  2021.  Postconvalescent SARS-CoV-2 IgG and Neutralizing Antibodies are Elevated in Individuals with Poor Metabolic Health.. J Clin Endocrinol Metab. 106(5):e2025-e2034.
Liu W, Russell RM, Bibollet-Ruche F, Skelly AN, Sherrill-Mix S, Freeman DA, Stoltz R, Lindemuth E, Lee F-H, Sterrett S et al..  2021.  Predictors of Nonseroconversion after SARS-CoV-2 Infection.. Emerg Infect Dis. 27(9):2454-2458.
Giardina SF, Valdambrini E, J Warren D, Barany F.  2021.  PROTACs: Promising Approaches for Epigenetic Strategies to Overcome Drug Resistance.. Curr Cancer Drug Targets. 21(4):306-325.
Yu EYoung, Zahid SS, Aloe S, Falck-Pedersen E, Zhou XKathy, Cheung N-KV, Lue NF.  2021.  Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology.. Commun Biol. 4(1):1315.
Wang H, Xu M, Engelhart CA, Zhang X, Yan B, Pan M, Xu Y, Fan S, Liu R, Xu L et al..  2021.  Rediscovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis.. J Biol Chem. 296:100257.
Chen X, Lee SKoo, Song M, Zhang T, Han MShin, Chen Y-T, Chen Z, Ma X, Tung C-H, Du Y-CNancy.  2021.  RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment.. Mol Ther Oncolytics. 23:277-287.
Ngwa CJ, Gross MR, Musabyimana J-P, Pradel G, Deitsch KW.  2021.  The Role of the Histone Methyltransferase PfSET10 in Antigenic Variation by Malaria Parasites: a Cautionary Tale.. mSphere. 6(1)