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Found 16 results
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Hillen, W
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2001
Schubert P
,
Schnappinger D
,
Pfleiderer K
,
Hillen W
. 2001.
Identification of a stability determinant on the edge of the Tet repressor four-helix bundle dimerization motif.
.
Biochemistry. 40(11):3257-63.
2000
Orth P
,
Schnappinger D
,
Hillen W
,
Saenger W
,
Hinrichs W
. 2000.
Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.
.
Nat Struct Biol. 7(3):215-9.
1999
Orth P
,
Schnappinger D
,
Sum PE
,
Ellestad GA
,
Hillen W
,
Saenger W
,
Hinrichs W
. 1999.
Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.
.
J Mol Biol. 285(2):455-61.
Baron U
,
Schnappinger D
,
Helbl V
,
Gossen M
,
Hillen W
,
Bujard H
. 1999.
Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.
.
Proc Natl Acad Sci U S A. 96(3):1013-8.
Schnappinger D
,
Schubert P
,
Berens C
,
Pfleiderer K
,
Hillen W
. 1999.
Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.
.
J Biol Chem. 274(10):6405-10.
1998
Orth P
,
Cordes F
,
Schnappinger D
,
Hillen W
,
Saenger W
,
Hinrichs W
. 1998.
Conformational changes of the Tet repressor induced by tetracycline trapping.
.
J Mol Biol. 279(2):439-47.
Schnappinger D
,
Schubert P
,
Pfleiderer K
,
Hillen W
. 1998.
Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.
.
EMBO J. 17(2):535-43.
1997
Schirmer F
,
Ehrt S
,
Hillen W
. 1997.
Expression, inducer spectrum, domain structure, and function of MopR, the regulator of phenol degradation in Acinetobacter calcoaceticus NCIB8250.
.
J Bacteriol. 179(4):1329-36.
Berens C
,
Schnappinger D
,
Hillen W
. 1997.
The role of the variable region in Tet repressor for inducibility by tetracycline.
.
J Biol Chem. 272(11):6936-42.
1996
Ettner N
,
Müller G
,
Berens C
,
Backes H
,
Schnappinger D
,
Schreppel T
,
Pfleiderer K
,
Hillen W
. 1996.
Fast large-scale purification of tetracycline repressor variants from overproducing Escherichia coli strains.
.
J Chromatogr A. 742(1-2):95-105.
Schnappinger D
,
Hillen W
. 1996.
Tetracyclines: antibiotic action, uptake, and resistance mechanisms.
.
Arch Microbiol. 165(6):359-69.
1995
Schnappinger D
,
Geissdörfer W
,
Sizemore C
,
Hillen W
. 1995.
Extracellular expression of native human anti-lysozyme fragments in Staphylococcus carnosus.
.
FEMS Microbiol Lett. 129(2-3):121-7.
Ehrt S
,
Schirmer F
,
Hillen W
. 1995.
Genetic organization, nucleotide sequence and regulation of expression of genes encoding phenol hydroxylase and catechol 1,2-dioxygenase in Acinetobacter calcoaceticus NCIB8250.
.
Mol Microbiol. 18(1):13-20.
Geissdörfer W
,
Frosch SC
,
Haspel G
,
Ehrt S
,
Hillen W
. 1995.
Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1.
.
Microbiology (Reading). 141 ( Pt 6):1425-32.
1994
Ehrt S
,
Ornston LN
,
Hillen W
. 1994.
RpoN (sigma 54) is required for conversion of phenol to catechol in Acinetobacter calcoaceticus.
.
J Bacteriol. 176(12):3493-9.
Ehrt S
,
Hillen W
. 1994.
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase from Acinetobacter calcoaceticus.
.
FEMS Microbiol Lett. 117(2):137-42.