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Publications

Found 21 results
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2020
Vanheer LN, Zhang H, Lin G, Kafsack BFC.  2020.  Activity of Epigenetic Inhibitors against Plasmodium falciparum Asexual and Sexual Blood Stages.. Antimicrob Agents Chemother. 64(7)
Matthews KA, Senagbe KM, Nötzel C, Gonzales CA, Tong X, Rijo-Ferreira F, Bhanu NV, Miguel-Blanco C, Lafuente-Monasterio MJose, Garcia BA et al..  2020.  Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases.. ACS Infect Dis. 6(5):1058-1075.
2019
McLean KJarrod, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT et al..  2019.  Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.. Sci Rep. 9(1):13131.
Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong T-T et al..  2019.  Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.. J Med Chem. 62(13):6137-6145.
Bancells C, Llorà-Batlle O, Poran A, Nötzel C, Rovira-Graells N, Elemento O, Kafsack BFC, Cortés A.  2019.  Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.. Nat Microbiol. 4(1):144-154.
2018
Nötzel C, Poran A, Kafsack BFC.  2018.  Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites.. Trends Parasitol. 34(9):731-734.
2017
Poran A, Nötzel C, Aly O, Mencia-Trinchant N, Harris CT, Guzman ML, Hassane DC, Elemento O, Kafsack BFC.  2017.  Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.. Nature. 551(7678):95-99.
2014
Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R et al..  2014.  A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.. Nature. 507(7491):253-257.
Coleman BI, Skillman KM, H Y Jiang R, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M et al..  2014.  A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.. Cell Host Microbe. 16(2):177-186.
Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA et al..  2014.  A transcriptional switch underlies commitment to sexual development in malaria parasites.. Nature. 507(7491):248-52.
2013
Carter LM, Kafsack BFC, Llinás M, Mideo N, Pollitt LC, Reece SE.  2013.  Stress and sex in malaria parasites: Why does commitment vary? Evol Med Public Health. 2013(1):135-47.
Painter HJ, Altenhofen LM, Kafsack BFC, Llinás M.  2013.  Whole-genome analysis of Plasmodium spp. Utilizing a new agilent technologies DNA microarray platform.. Methods Mol Biol. 923:213-9.
2010
Kafsack BFC, Carruthers VB.  2010.  Apicomplexan perforin-like proteins.. Commun Integr Biol. 3(1):18-23.
Kafsack BFC, Llinás M.  2010.  Eating at the table of another: metabolomics of host-parasite interactions.. Cell Host Microbe. 7(2):90-9.
Lagal V, Binder EM, Huynh M-H, Kafsack BFC, Harris PK, Diez R, Chen D, Cole RN, Carruthers VB, Kim K.  2010.  Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites.. Cell Microbiol. 12(12):1792-808.
2009
Kafsack BFC, Pena JDO, Coppens I, Ravindran S, Boothroyd JC, Carruthers VB.  2009.  Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.. Science. 323(5913):530-3.
2007
Kafsack BFC, Carruthers VB, Pineda FJ.  2007.  Kinetic modeling of Toxoplasma gondii invasion.. J Theor Biol. 249(4):817-25.
2005
Zhou XW, Kafsack BFC, Cole RN, Beckett P, Shen RF, Carruthers VB.  2005.  The opportunistic pathogen Toxoplasma gondii deploys a diverse legion of invasion and survival proteins.. J Biol Chem. 280(40):34233-44.
2004
Harper JM, Zhou XW, Pszenny V, Kafsack BFC, Carruthers VB.  2004.  The novel coccidian micronemal protein MIC11 undergoes proteolytic maturation by sequential cleavage to remove an internal propeptide.. Int J Parasitol. 34(9):1047-58.
2003
Seamons A, Sutton J, Bai D, Baird E, Bonn N, Kafsack BFC, Shabanowitz J, Hunt DF, Beeson C, Goverman J.  2003.  Competition between two MHC binding registers in a single peptide processed from myelin basic protein influences tolerance and susceptibility to autoimmunity.. J Exp Med. 197(10):1391-7.