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Publications

Found 16 results
Author Title Type [ Year(Desc)]
Filters: Author is Hillen, W  [Clear All Filters]
1994
Ehrt S, Ornston LN, Hillen W.  1994.  RpoN (sigma 54) is required for conversion of phenol to catechol in Acinetobacter calcoaceticus.. J Bacteriol. 176(12):3493-9.
Ehrt S, Hillen W.  1994.  UDP-N-acetylglucosamine 1-carboxyvinyl-transferase from Acinetobacter calcoaceticus.. FEMS Microbiol Lett. 117(2):137-42.
1996
Ettner N, Müller G, Berens C, Backes H, Schnappinger D, Schreppel T, Pfleiderer K, Hillen W.  1996.  Fast large-scale purification of tetracycline repressor variants from overproducing Escherichia coli strains.. J Chromatogr A. 742(1-2):95-105.
Schnappinger D, Hillen W.  1996.  Tetracyclines: antibiotic action, uptake, and resistance mechanisms.. Arch Microbiol. 165(6):359-69.
1997
Schirmer F, Ehrt S, Hillen W.  1997.  Expression, inducer spectrum, domain structure, and function of MopR, the regulator of phenol degradation in Acinetobacter calcoaceticus NCIB8250.. J Bacteriol. 179(4):1329-36.
Berens C, Schnappinger D, Hillen W.  1997.  The role of the variable region in Tet repressor for inducibility by tetracycline.. J Biol Chem. 272(11):6936-42.
1998
Orth P, Cordes F, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  1998.  Conformational changes of the Tet repressor induced by tetracycline trapping.. J Mol Biol. 279(2):439-47.
Schnappinger D, Schubert P, Pfleiderer K, Hillen W.  1998.  Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.. EMBO J. 17(2):535-43.
1999
Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W.  1999.  Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. J Mol Biol. 285(2):455-61.
Baron U, Schnappinger D, Helbl V, Gossen M, Hillen W, Bujard H.  1999.  Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.. Proc Natl Acad Sci U S A. 96(3):1013-8.
Schnappinger D, Schubert P, Berens C, Pfleiderer K, Hillen W.  1999.  Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.. J Biol Chem. 274(10):6405-10.
2000
Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  2000.  Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.. Nat Struct Biol. 7(3):215-9.
2001
Schubert P, Schnappinger D, Pfleiderer K, Hillen W.  2001.  Identification of a stability determinant on the edge of the Tet repressor four-helix bundle dimerization motif.. Biochemistry. 40(11):3257-63.