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Found 19 results
Author
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Klasse, Per Johan
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2015
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
2012
Ketas TJ
,
Holuigue S
,
Matthews K
,
Moore JP
,
Klasse PJohan
. 2012.
Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors.
.
Virology. 422(1):22-36.
Klasse PJohan
,
Sanders RW
,
Cerutti A
,
Moore JP
. 2012.
How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?
AIDS Res Hum Retroviruses. 28(1):1-15.
R Malcolm K
,
Veazey RS
,
Geer L
,
Lowry D
,
Fetherston SM
,
Murphy DJ
,
Boyd P
,
Major I
,
Shattock RJ
,
Klasse PJohan
et al.
. 2012.
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.
.
Antimicrob Agents Chemother. 56(5):2251-8.
Melchers M
,
Bontjer I
,
Tong T
,
P Y Chung N
,
Klasse PJohan
,
Eggink D
,
Montefiori DC
,
Gentile M
,
Cerutti A
,
Olson WC
et al.
. 2012.
Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.
.
J Virol. 86(5):2488-500.
2011
Burton DR
,
Hessell AJ
,
Keele BF
,
Klasse PJohan
,
Ketas TA
,
Moldt B
,
D Dunlop C
,
Poignard P
,
Doyle LA
,
Cavacini L
et al.
. 2011.
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody.
.
Proc Natl Acad Sci U S A. 108(27):11181-6.
Berro R
,
Klasse PJohan
,
Lascano D
,
Flegler A
,
Nagashima KA
,
Sanders RW
,
Sakmar TP
,
Hope TJ
,
Moore JP
. 2011.
Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.
.
J Virol. 85(16):8227-40.
Forbes CJ
,
Lowry D
,
Geer L
,
Veazey RS
,
Shattock RJ
,
Klasse PJohan
,
Mitchnick M
,
Goldman L
,
Doyle LA
,
Muldoon BCO
et al.
. 2011.
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
.
J Control Release. 156(2):161-9.
Anastassopoulou CG
,
Ketas TJ
,
Depetris RS
,
Thomas AM
,
Klasse PJohan
,
Moore JP
. 2011.
Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41.
.
Virology. 413(1):47-59.
Harris A
,
Borgnia MJ
,
Shi D
,
Bartesaghi A
,
He H
,
Pejchal R
,
Kang YKenneth
,
Depetris R
,
Marozsan AJ
,
Sanders RW
et al.
. 2011.
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.
.
Proc Natl Acad Sci U S A. 108(28):11440-5.
2009
Banerjee K
,
Andjelic S
,
Klasse PJohan
,
Kang Y
,
Sanders RW
,
Michael E
,
Durso RJ
,
Ketas TJ
,
Olson WC
,
Moore JP
. 2009.
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
.
Virology. 389(1-2):108-21.
Pugach P
,
Ray N
,
Klasse PJohan
,
Ketas TJ
,
Michael E
,
Doms RW
,
Lee B
,
Moore JP
. 2009.
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
.
Virology. 387(2):296-302.
Anastassopoulou CG
,
Ketas TJ
,
Klasse PJohan
,
Moore JP
. 2009.
Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.
.
Proc Natl Acad Sci U S A. 106(13):5318-23.
W Horne S
,
Johnson LM
,
Ketas TJ
,
Klasse PJohan
,
Lu M
,
Moore JP
,
Gellman SH
. 2009.
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
.
Proc Natl Acad Sci U S A. 106(35):14751-6.
2008
Klasse PJohan
,
Shattock R
,
Moore JP
. 2008.
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission.
.
Annu Rev Med. 59:455-71.
Veazey RS
,
Ketas TA
,
Klasse PJohan
,
Davison DK
,
Singletary M
,
Green LC
,
Greenberg ML
,
Moore JP
. 2008.
Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249.
.
Proc Natl Acad Sci U S A. 105(30):10531-6.
2007
Ketas TJ
,
Schader SM
,
Zurita J
,
Teo E
,
Polonis V
,
Lu M
,
Klasse PJohan
,
Moore JP
. 2007.
Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes.
.
Virology. 364(2):431-40.
2005
Veazey RS
,
Springer MS
,
Marx PA
,
Dufour J
,
Klasse PJohan
,
Moore JP
. 2005.
Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor.
.
Nat Med. 11(12):1293-4.
Veazey RS
,
Klasse PJohan
,
Schader SM
,
Hu Q
,
Ketas TJ
,
Lu M
,
Marx PA
,
Dufour J
,
Colonno RJ
,
Shattock RJ
et al.
. 2005.
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.
.
Nature. 438(7064):99-102.