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Publications

Found 985 results
Author Title Type [ Year(Asc)]
2016
Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G et al..  2016.  The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.. Oncotarget. 7(29):45597-45607.
Lin K, O'Brien KM, Trujillo C, Wang R, Wallach JB, Schnappinger D, Ehrt S.  2016.  Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense.. PLoS Pathog. 12(6):e1005675.
Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J et al..  2016.  N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 113(31):E4523-30.
Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Quezada LLopez, Somersan S, Warrier T, Little D, Pingle M et al..  2016.  Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.. J Med Chem. 59(13):6027-44.
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Resto YAlemán, Alsibaee A, Alzualde A et al..  2016.  Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.. PLoS Pathog. 12(7):e1005763.
Yan W, Ding A, Kim H-J, Zheng H, Wei F, Ma X.  2016.  Progranulin Controls Sepsis via C/EBPα-Regulated Il10 Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation.. J Immunol. 197(8):3393-3405.
Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan C.  2016.  Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.. Proc Natl Acad Sci U S A. 113(49):E7947-E7956.
Chauhan R, Ravi J, Datta P, Chen T, Schnappinger D, Bassler KE, Balázsi G, Gennaro MLaura.  2016.  Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis.. Nat Commun. 7:11062.
Li W, Obregón-Henao A, Wallach JB, E North J, Lee RE, Gonzalez-Juarrero M, Schnappinger D, Jackson M.  2016.  Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.. Antimicrob Agents Chemother. 60(9):5198-207.
Korte J, Alber M, Trujillo CM, Syson K, Koliwer-Brandl H, Deenen R, Köhrer K, DeJesus MA, Hartman T, Jacobs WR et al..  2016.  Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.. PLoS Pathog. 12(12):e1006043.
2015
Mackley EC, Houston S, Marriott CL, Halford EE, Lucas B, Cerovic V, Filbey KJ, Maizels RM, Hepworth MR, Sonnenberg GF et al..  2015.  CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.. Nat Commun. 6:5862.
Frykman PK, Nordenskjöld A, Kawaguchi A, Hui TT, Granström AL, Cheng Z, Tang J, Underhill DM, Iliev ID, Funari VA et al..  2015.  Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.. PLoS One. 10(4):e0124172.
Steinberg-Neifach O, Wellington K, Vazquez L, Lue NF.  2015.  Combinatorial recognition of a complex telomere repeat sequence by the Candida parapsilosis Cdc13AB heterodimer.. Nucleic Acids Res. 43(4):2164-76.
Schnappinger D, O'Brien KM, Ehrt S.  2015.  Construction of conditional knockdown mutants in mycobacteria.. Methods Mol Biol. 1285:151-75.
Nathan C.  2015.  Cooperative development of antimicrobials: looking back to look ahead.. Nat Rev Microbiol. 13(10):651-7.
Iliev ID.  2015.  Dectin-1 Exerts Dual Control in the Gut.. Cell Host Microbe. 18(2):139-41.
Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J.  2015.  The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. Nat Immunol. 16(6):599-608.
Goodsmith N, Guo XV, Vandal OH, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P et al..  2015.  Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.. PLoS Pathog. 11(2):e1004645.
Maksymiuk C, Balakrishnan A, Bryk R, Rhee KY, Nathan C.  2015.  E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.. Proc Natl Acad Sci U S A. 112(43):E5834-43.
Ukaegbu UE, Deitsch KW.  2015.  The Emerging Role for RNA Polymerase II in Regulating Virulence Gene Expression in Malaria Parasites.. PLoS Pathog. 11(7):e1004926.
Dai R, Geders TW, Liu F, Park SWoong, Schnappinger D, Aldrich CC, Finzel BC.  2015.  Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.. J Med Chem. 58(13):5208-17.
de Sena-Tomás C, Yu EYoung, Calzada A, Holloman WK, Lue NF, Pérez-Martín J.  2015.  Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.. Nucleic Acids Res. 43(4):2138-51.
Schnappinger D.  2015.  Genetic Approaches to Facilitate Antibacterial Drug Development.. Cold Spring Harb Perspect Med. 5(7):a021139.
Murray HW, Mitchell-Flack M, Zheng H, Ma X.  2015.  Granzyme-mediated regulation of host defense in the liver in experimental Leishmania donovani infection.. Infect Immun. 83(2):702-12.
Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.