Microbiology and Immunology

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Found 18 results

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C

Orth P, Cordes F, Schnappinger D, Hillen W, Saenger W, Hinrichs W. 1998. Conformational changes of the Tet repressor induced by tetracycline trapping.. J Mol Biol. 279(2):439-47.

Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W. 1999. Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. J Mol Biol. 285(2):455-61.

Orth P, Alings C, Schnappinger D, Saenger W, Hinrichs W. 1998. Crystallization and preliminary X-ray analysis of the Tet-repressor/operator complex.. Acta Crystallogr D Biol Crystallogr. 54(Pt 1):99-100.

D

Schnappinger D, Schubert P, Pfleiderer K, Hillen W. 1998. Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.. EMBO J. 17(2):535-43.

E

Kaps I, Ehrt S, Seeber S, Schnappinger D, Martin C, Riley LW, Niederweis M. 2001. Energy transfer between fluorescent proteins using a co-expression system in Mycobacterium smegmatis.. Gene. 278(1-2):115-24.

Schnappinger D, Geissdörfer W, Sizemore C, Hillen W. 1995. Extracellular expression of native human anti-lysozyme fragments in Staphylococcus carnosus.. FEMS Microbiol Lett. 129(2-3):121-7.

F

Ettner N, Müller G, Berens C, Backes H, Schnappinger D, Schreppel T, Pfleiderer K, Hillen W. 1996. Fast large-scale purification of tetracycline repressor variants from overproducing Escherichia coli strains.. J Chromatogr A. 742(1-2):95-105.

Wilson M, Voskuil M, Schnappinger D, Schoolnik GK. 2001. Functional Genomics of Mycobacterium tuberculosis Using DNA Microarrays.. Methods Mol Med. 54:335-57.

G

Baron U, Schnappinger D, Helbl V, Gossen M, Hillen W, Bujard H. 1999. Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.. Proc Natl Acad Sci U S A. 96(3):1013-8.

I

Schubert P, Schnappinger D, Pfleiderer K, Hillen W. 2001. Identification of a stability determinant on the edge of the Tet repressor four-helix bundle dimerization motif.. Biochemistry. 40(11):3257-63.

R

Sherman DR, Voskuil M, Schnappinger D, Liao R, Harrell MI, Schoolnik GK. 2001. Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin.. Proc Natl Acad Sci U S A. 98(13):7534-9.

Voskuil MI, Schnappinger D, Rutherford R, Liu Y, Schoolnik GK. 2004. Regulation of the Mycobacterium tuberculosis PE/PPE genes.. Tuberculosis (Edinb). 84(3-4):256-62.

Ehrt S, Schnappinger D, Bekiranov S, Drenkow J, Shi S, Gingeras TR, Gaasterland T, Schoolnik G, Nathan C. 2001. Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase.. J Exp Med. 194(8):1123-40.

Berens C, Schnappinger D, Hillen W. 1997. The role of the variable region in Tet repressor for inducibility by tetracycline.. J Biol Chem. 272(11):6936-42.

S

Schnappinger D, Schubert P, Berens C, Pfleiderer K, Hillen W. 1999. Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.. J Biol Chem. 274(10):6405-10.

Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W. 2000. Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.. Nat Struct Biol. 7(3):215-9.

T

Schnappinger D, Hillen W. 1996. Tetracyclines: antibiotic action, uptake, and resistance mechanisms.. Arch Microbiol. 165(6):359-69.

W

Schoolnik GK, Voskuil MI, Schnappinger D, Yildiz FH, Meibom K, Dolganov NA, Wilson MA, Chong KH. 2001. Whole genome DNA microarray expression analysis of biofilm development by Vibrio cholerae O1 E1 Tor.. Methods Enzymol. 336:3-18.