Microbiology and Immunology

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Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA et al..  2014.  A transcriptional switch underlies commitment to sexual development in malaria parasites.. Nature. 507(7491):248-52.
Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, Dolganov G, Efron B, Butcher PD, Nathan C et al..  2003.  Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.. J Exp Med. 198(5):693-704.
Falck-Pedersen E, Logan J, Shenk T, Darnell JE.  1985.  Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element.. Cell. 40(4):897-905.
Citron B, Falck-Pedersen E, Salditt-Georgieff M, Darnell JE.  1984.  Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse beta-globin (major) gene.. Nucleic Acids Res. 12(22):8723-31.
Lagal V, Binder EM, Huynh M-H, Kafsack BFC, Harris PK, Diez R, Chen D, Cole RN, Carruthers VB, Kim K.  2010.  Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites.. Cell Microbiol. 12(12):1792-808.
Gengenbacher M, Zimmerman MD, Sarathy JP, Kaya F, Wang H, Mina M, Carter C, Hossen MAmir, Su H, Trujillo C et al..  2020.  Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.. Antimicrob Agents Chemother. 64(5)
Kapitskaya MZ, Dittmer NT, Deitsch KW, Cho WL, Taylor DG, Leff T, Raikhel AS.  1998.  Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito.. J Biol Chem. 273(45):29801-10.
Kapitskaya MZ, Dittmer NT, Deitsch KW, Cho WL, Taylor DG, Leff T, Raikhel AS.  1998.  Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito.. J Biol Chem. 273(45):29801-10.
Hsu M, McEachern MJ, Dandjinou AT, Tzfati Y, Orr E, Blackburn EH, Lue NF.  2007.  Telomerase core components protect Candida telomeres from aberrant overhang accumulation.. Proc Natl Acad Sci U S A. 104(28):11682-7.
Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S.  2015.  Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.. Proc Natl Acad Sci U S A. 112(38):11935-40.
Tiwari D, Park SWoong, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M, Ho HPin, Engelhart CA et al..  2018.  Targeting protein biotinylation enhances tuberculosis chemotherapy.. Sci Transl Med. 10(438)
Tiwari D, Park SWoong, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M, Ho HPin, Engelhart CA et al..  2018.  Targeting protein biotinylation enhances tuberculosis chemotherapy.. Sci Transl Med. 10(438)
Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al..  2015.  Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.
Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al..  2015.  Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.
Templeton TJ, Deitsch KW.  2005.  Targeting malaria parasite proteins to the erythrocyte.. Trends Parasitol. 21(9):399-402.
Wang K-J, Wang C, Dai L-H, Yang J, Huang H, Ma X-J, Zhou Z, Yang Z-Y, Xu W-D, Hua M-M et al..  2019.  Targeting an Autocrine Regulatory Loop in Cancer Stem-like Cells Impairs the Progression and Chemotherapy Resistance of Bladder Cancer.. Clin Cancer Res. 25(3):1070-1086.
Rafiq S, Yeku OO, Jackson HJ, Purdon TJ, van Leeuwen DG, Drakes DJ, Song M, Miele MM, Li Z, Wang P et al..  2018.  Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.. Nat Biotechnol. 36(9):847-856.
Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED et al..  2015.  Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.. ACS Chem Biol. 10(2):364-71.
Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al..  2015.  Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.
Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang X-Y.  2005.  Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.. Proc Natl Acad Sci U S A. 102(10):3772-6.
R Malcolm K, Veazey RS, Geer L, Lowry D, Fetherston SM, Murphy DJ, Boyd P, Major I, Shattock RJ, Klasse PJohan et al..  2012.  Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.. Antimicrob Agents Chemother. 56(5):2251-8.
Liu F, Dawadi S, Maize KM, Dai R, Park SWoong, Schnappinger D, Finzel BC, Aldrich CC.  2017.  Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem. 60(13):5507-5520.
Liu F, Dawadi S, Maize KM, Dai R, Park SWoong, Schnappinger D, Finzel BC, Aldrich CC.  2017.  Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem. 60(13):5507-5520.
Liu J, Deng Y, Dey AK, Moore JP, Lu M.  2009.  Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation.. Biochemistry. 48(13):2915-23.
Liu J, Deng Y, Dey AK, Moore JP, Lu M.  2009.  Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation.. Biochemistry. 48(13):2915-23.