Submitted by mam2155 on March 24, 2014 - 4:11pm
| Title | Targeting malaria parasite proteins to the erythrocyte. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Templeton TJ, Deitsch KW |
| Journal | Trends Parasitol |
| Volume | 21 |
| Issue | 9 |
| Pagination | 399-402 |
| Date Published | 2005 Sep |
| ISSN | 1471-4922 |
| Keywords | Amino Acid Sequence, Animals, Erythrocytes, Genes, Protozoan, Host-Parasite Interactions, Humans, Malaria, Falciparum, Plasmodium falciparum, Protozoan Proteins, Sequence Alignment, Vacuoles |
| Abstract | The intraerythrocytic stages of the protozoan parasite Plasmodium falciparum reside within a parasitophorous vacuole (PV) and set up unique "extraparasite, intraerythrocyte" protein-trafficking pathways that target parasite-encoded proteins to the erythrocyte cytoplasm and cell surface. Two recent articles report the identification of trafficking motifs that regulate the transport of parasite-encoded proteins across the PV. These articles greatly aid the annotation of the parasite "secretome" catalog of proteins that are targeted to the erythrocyte cytoplasm or cell membrane. |
| DOI | 10.1016/j.pt.2005.07.006 |
| Alternate Journal | Trends Parasitol |
| PubMed ID | 16046185 |