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Found 18 results
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Sanders, Rogier W
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Journal Article
Dey AK
,
Cupo A
,
Ozorowski G
,
Sharma VK
,
Behrens A-J
,
Go EP
,
Ketas TJ
,
Yasmeen A
,
Klasse PJ
,
Sayeed E
et al.
. 2018.
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
.
Biotechnol Bioeng. 115(4):885-899.
van Montfort T
,
Melchers M
,
Isik G
,
Menis S
,
Huang P-S
,
Matthews K
,
Michael E
,
Berkhout B
,
Schief WR
,
Moore JP
et al.
. 2011.
A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses.
.
J Biol Chem. 286(25):22250-61.
Ringe RP
,
Pugach P
,
Cottrell CA
,
LaBranche CC
,
Seabright GE
,
Ketas TJ
,
Ozorowski G
,
Kumar S
,
Schorcht A
,
van Gils MJ
et al.
. 2019.
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.
.
J Virol. 93(4)
Banerjee K
,
Andjelic S
,
Klasse PJohan
,
Kang Y
,
Sanders RW
,
Michael E
,
Durso RJ
,
Ketas TJ
,
Olson WC
,
Moore JP
. 2009.
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
.
Virology. 389(1-2):108-21.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Klasse PJohan
,
Sanders RW
,
Cerutti A
,
Moore JP
. 2012.
How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?
AIDS Res Hum Retroviruses. 28(1):1-15.
Banerjee K
,
Klasse PJ
,
Sanders RW
,
Pereyra F
,
Michael E
,
Lu M
,
Walker BD
,
Moore JP
. 2010.
IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines.
.
AIDS Res Hum Retroviruses. 26(4):445-58.
Ringe RP
,
Yasmeen A
,
Ozorowski G
,
Go EP
,
Pritchard LK
,
Guttman M
,
Ketas TA
,
Cottrell CA
,
Wilson IA
,
Sanders RW
et al.
. 2015.
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.
.
J Virol. 89(23):12189-210.
Eggink D
,
Melchers M
,
Wuhrer M
,
van Montfort T
,
Dey AK
,
Naaijkens BA
,
David KB
,
Le Douce V
,
Deelder AM
,
Kang K
et al.
. 2010.
Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.
.
Virology. 401(2):236-47.
Berro R
,
Klasse PJohan
,
Lascano D
,
Flegler A
,
Nagashima KA
,
Sanders RW
,
Sakmar TP
,
Hope TJ
,
Moore JP
. 2011.
Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.
.
J Virol. 85(16):8227-40.
Sanders RW
,
Moore JP
. 2017.
Native-like Env trimers as a platform for HIV-1 vaccine design.
.
Immunol Rev. 275(1):161-182.
Pejchal R
,
Doores KJ
,
Walker LM
,
Khayat R
,
Huang P-S
,
Wang S-K
,
Stanfield RL
,
Julien J-P
,
Ramos A
,
Crispin M
et al.
. 2011.
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
.
Science. 334(6059):1097-103.
Melchers M
,
Matthews K
,
de Vries RP
,
Eggink D
,
van Montfort T
,
Bontjer I
,
van de Sandt C
,
David K
,
Berkhout B
,
Moore JP
et al.
. 2011.
A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells.
.
Retrovirology. 8:48.
Bontjer I
,
Melchers M
,
Eggink D
,
David K
,
Moore JP
,
Berkhout B
,
Sanders RW
. 2010.
Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.
.
J Biol Chem. 285(47):36456-70.
Melchers M
,
Bontjer I
,
Tong T
,
P Y Chung N
,
Klasse PJohan
,
Eggink D
,
Montefiori DC
,
Gentile M
,
Cerutti A
,
Olson WC
et al.
. 2012.
Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.
.
J Virol. 86(5):2488-500.
Harris A
,
Borgnia MJ
,
Shi D
,
Bartesaghi A
,
He H
,
Pejchal R
,
Kang YKenneth
,
Depetris R
,
Marozsan AJ
,
Sanders RW
et al.
. 2011.
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.
.
Proc Natl Acad Sci U S A. 108(28):11440-5.
Berro R
,
Sanders RW
,
Lu M
,
Klasse PJ
,
Moore JP
. 2009.
Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
.
PLoS Pathog. 5(8):e1000548.