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Found 47 results
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Moore, John P
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2010
Eggink D
,
Melchers M
,
Wuhrer M
,
van Montfort T
,
Dey AK
,
Naaijkens BA
,
David KB
,
Le Douce V
,
Deelder AM
,
Kang K
et al.
. 2010.
Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.
.
Virology. 401(2):236-47.
Veazey RS
,
Ketas TJ
,
Dufour J
,
Moroney-Rasmussen T
,
Green LC
,
Klasse PJ
,
Moore JP
. 2010.
Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.
.
J Infect Dis. 202(5):739-44.
Liu J
,
Deng Y
,
Li Q
,
Dey AK
,
Moore JP
,
Lu M
. 2010.
Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion.
.
J Virol. 84(1):201-9.
Bontjer I
,
Melchers M
,
Eggink D
,
David K
,
Moore JP
,
Berkhout B
,
Sanders RW
. 2010.
Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.
.
J Biol Chem. 285(47):36456-70.
2009
Ingallinella P
,
Bianchi E
,
Ladwa NA
,
Wang Y-J
,
Hrin R
,
Veneziano M
,
Bonelli F
,
Ketas TJ
,
Moore JP
,
Miller MD
et al.
. 2009.
Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency.
.
Proc Natl Acad Sci U S A. 106(14):5801-6.
Dey AK
,
David KB
,
Lu M
,
Moore JP
. 2009.
Biochemical and biophysical comparison of cleaved and uncleaved soluble, trimeric HIV-1 envelope glycoproteins.
.
Virology. 385(1):275-81.
Banerjee K
,
Andjelic S
,
Klasse PJohan
,
Kang Y
,
Sanders RW
,
Michael E
,
Durso RJ
,
Ketas TJ
,
Olson WC
,
Moore JP
. 2009.
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
.
Virology. 389(1-2):108-21.
Pugach P
,
Ray N
,
Klasse PJohan
,
Ketas TJ
,
Michael E
,
Doms RW
,
Lee B
,
Moore JP
. 2009.
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
.
Virology. 387(2):296-302.
Moore JP
,
Kuritzkes DR
. 2009.
A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitors.
.
Curr Opin HIV AIDS. 4(2):118-24.
Anastassopoulou CG
,
Ketas TJ
,
Klasse PJohan
,
Moore JP
. 2009.
Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.
.
Proc Natl Acad Sci U S A. 106(13):5318-23.
W Horne S
,
Johnson LM
,
Ketas TJ
,
Klasse PJohan
,
Lu M
,
Moore JP
,
Gellman SH
. 2009.
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
.
Proc Natl Acad Sci U S A. 106(35):14751-6.
Kang YKenneth
,
Andjelic S
,
Binley JM
,
Crooks ET
,
Franti M
,
Iyer SPrasad N
,
Donovan GP
,
Dey AK
,
Zhu P
,
Roux KH
et al.
. 2009.
Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1.
.
Vaccine. 27(37):5120-32.
Liu J
,
Deng Y
,
Dey AK
,
Moore JP
,
Lu M
. 2009.
Structure of the HIV-1 gp41 membrane-proximal ectodomain region in a putative prefusion conformation.
.
Biochemistry. 48(13):2915-23.
Berro R
,
Sanders RW
,
Lu M
,
Klasse PJ
,
Moore JP
. 2009.
Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
.
PLoS Pathog. 5(8):e1000548.
2008
Klasse PJohan
,
Shattock R
,
Moore JP
. 2008.
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission.
.
Annu Rev Med. 59:455-71.
Pugach P
,
Ketas TJ
,
Michael E
,
Moore JP
. 2008.
Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors.
.
Virology. 377(2):401-7.
Dey AK
,
David KB
,
Ray N
,
Ketas TJ
,
Klasse PJ
,
Doms RW
,
Moore JP
. 2008.
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus.
.
Virology. 372(1):187-200.
Veazey RS
,
Ketas TA
,
Klasse PJohan
,
Davison DK
,
Singletary M
,
Green LC
,
Greenberg ML
,
Moore JP
. 2008.
Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249.
.
Proc Natl Acad Sci U S A. 105(30):10531-6.
2007
Ketas TJ
,
Schader SM
,
Zurita J
,
Teo E
,
Polonis V
,
Lu M
,
Klasse PJohan
,
Moore JP
. 2007.
Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes.
.
Virology. 364(2):431-40.
Dey AK
,
David KB
,
Klasse PJ
,
Moore JP
. 2007.
Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1.
.
Virology. 360(1):199-208.
2005
Veazey RS
,
Springer MS
,
Marx PA
,
Dufour J
,
Klasse PJohan
,
Moore JP
. 2005.
Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor.
.
Nat Med. 11(12):1293-4.
Veazey RS
,
Klasse PJohan
,
Schader SM
,
Hu Q
,
Ketas TJ
,
Lu M
,
Marx PA
,
Dufour J
,
Colonno RJ
,
Shattock RJ
et al.
. 2005.
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.
.
Nature. 438(7064):99-102.
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