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Found 85 results
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Ehrt, Sabine
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2003
Shimono N
,
Morici L
,
Casali N
,
Cantrell S
,
Sidders B
,
Ehrt S
,
Riley LW
. 2003.
Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon.
.
Proc Natl Acad Sci U S A. 100(26):15918-23.
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by alkaline lysis.
.
Methods Mol Biol. 235:75-8.
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by boiling lysis.
.
Methods Mol Biol. 235:79-82.
Shi S
,
Nathan C
,
Schnappinger D
,
Drenkow J
,
Fuortes M
,
Block E
,
Ding A
,
Gingeras TR
,
Schoolnik G
,
Akira S
et al.
. 2003.
MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.
.
J Exp Med. 198(7):987-97.
K Darwin H
,
Ehrt S
,
Gutierrez-Ramos J-C
,
Weich N
,
Nathan CF
. 2003.
The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.
.
Science. 302(5652):1963-6.
Schnappinger D
,
Ehrt S
,
Voskuil MI
,
Liu Y
,
Mangan JA
,
Monahan IM
,
Dolganov G
,
Efron B
,
Butcher PD
,
Nathan C
et al.
. 2003.
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.
.
J Exp Med. 198(5):693-704.
2005
Morris RP
,
Nguyen L
,
Gatfield J
,
Visconti K
,
Nguyen K
,
Schnappinger D
,
Ehrt S
,
Liu Y
,
Heifets L
,
Pieters J
et al.
. 2005.
Ancestral antibiotic resistance in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 102(34):12200-5.
Ehrt S
,
Guo XV
,
Hickey CM
,
Ryou M
,
Monteleone M
,
Riley LW
,
Schnappinger D
. 2005.
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor.
.
Nucleic Acids Res. 33(2):e21.
Shi S
,
Blumenthal A
,
Hickey CM
,
Gandotra S
,
Levy D
,
Ehrt S
. 2005.
Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.
.
J Immunol. 175(5):3318-28.
Hisert KB
,
MacCoss M
,
Shiloh MU
,
K Darwin H
,
Singh S
,
Jones RA
,
Ehrt S
,
Zhang Z
,
Gaffney BL
,
Gandotra S
et al.
. 2005.
A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.
.
Mol Microbiol. 56(5):1234-45.
Ding A
,
Yu H
,
Yang J
,
Shi S
,
Ehrt S
. 2005.
Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.
.
Immunology. 116(3):381-9.
Nathan C
,
Calingasan N
,
Nezezon J
,
Ding A
,
M Lucia S
,
La Perle K
,
Fuortes M
,
Lin M
,
Ehrt S
,
Kwon NSoo
et al.
. 2005.
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.
.
J Exp Med. 202(9):1163-9.
2006
Ehrt S
,
Schnappinger D
. 2006.
Controlling gene expression in mycobacteria.
.
Future Microbiol. 1(2):177-84.
Vandal OH
,
Gelb MH
,
Ehrt S
,
Nathan CF
. 2006.
Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.
.
Infect Immun. 74(3):1751-6.
Shi S
,
Ehrt S
. 2006.
Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.
.
Infect Immun. 74(1):56-63.
Schnappinger D
,
Schoolnik GK
,
Ehrt S
. 2006.
Expression profiling of host pathogen interactions: how Mycobacterium tuberculosis and the macrophage adapt to one another.
.
Microbes Infect. 8(4):1132-40.
Schnappinger D
,
Ehrt S
. 2006.
Introduction: genomic approaches in infectious diseases.
.
Microbes Infect. 8(6):1611-2.
2007
Gandotra S
,
Schnappinger D
,
Monteleone M
,
Hillen W
,
Ehrt S
. 2007.
In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.
.
Nat Med. 13(12):1515-20.
Stephanou NC
,
Gao F
,
Bongiorno P
,
Ehrt S
,
Schnappinger D
,
Shuman S
,
Glickman MS
. 2007.
Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.
.
J Bacteriol. 189(14):5237-46.
Ehrt S
,
Schnappinger D
. 2007.
Mycobacterium tuberculosis virulence: lipids inside and out.
.
Nat Med. 13(3):284-5.
Gandotra S
,
Jang S
,
Murray PJ
,
Salgame P
,
Ehrt S
. 2007.
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.
.
Infect Immun. 75(11):5127-34.
Guo XV
,
Monteleone M
,
Klotzsche M
,
Kamionka A
,
Hillen W
,
Braunstein M
,
Ehrt S
,
Schnappinger D
. 2007.
Silencing Mycobacterium smegmatis by using tetracycline repressors.
.
J Bacteriol. 189(13):4614-23.
2008
Boshoff HIM
,
Xu X
,
Tahlan K
,
Dowd CS
,
Pethe K
,
Camacho LR
,
Park T-H
,
Yun C-S
,
Schnappinger D
,
Ehrt S
et al.
. 2008.
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
.
J Biol Chem. 283(28):19329-41.
Vandal OH
,
Pierini LM
,
Schnappinger D
,
Nathan CF
,
Ehrt S
. 2008.
A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.
.
Nat Med. 14(8):849-54.
Bryk R
,
Gold B
,
Venugopal A
,
Singh J
,
Samy R
,
Pupek K
,
Cao H
,
Popescu C
,
Gurney M
,
Hotha S
et al.
. 2008.
Selective killing of nonreplicating mycobacteria.
.
Cell Host Microbe. 3(3):137-45.
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