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Found 188 results
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2017
Rock JM
,
Hopkins FF
,
Chavez A
,
Diallo M
,
Chase MR
,
Gerrick ER
,
Pritchard JR
,
Church GM
,
Rubin EJ
,
Sassetti CM
et al.
. 2017.
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
.
Nat Microbiol. 2:16274.
Saito K
,
Warrier T
,
Somersan-Karakaya S
,
Kaminski L
,
Mi J
,
Jiang X
,
Park S
,
Shigyo K
,
Gold B
,
Roberts J
et al.
. 2017.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
.
Proc Natl Acad Sci U S A. 114(24):E4832-E4840.
Poran A
,
Nötzel C
,
Aly O
,
Mencia-Trinchant N
,
Harris CT
,
Guzman ML
,
Hassane DC
,
Elemento O
,
Kafsack BFC
. 2017.
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.
.
Nature. 551(7678):95-99.
Liu F
,
Dawadi S
,
Maize KM
,
Dai R
,
Park SWoong
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2017.
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
.
J Med Chem. 60(13):5507-5520.
2018
McAulay K
,
Saito K
,
Warrier T
,
Walsh KFrances
,
Mathurin LDaniel
,
Royal-Mardi G
,
Lee MHee
,
Ocheretina O
,
Pape JWilliam
,
Fitzgerald DW
et al.
. 2018.
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
.
mBio. 9(6)
Oh S
,
Park Y
,
Engelhart CA
,
Wallach JB
,
Schnappinger D
,
Arora K
,
Manikkam M
,
Gac B
,
Wang H
,
Murgolo N
et al.
. 2018.
Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
.
J Med Chem. 61(22):9952-9965.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Wescott HH
,
Zuniga ES
,
Bajpai A
,
Trujillo C
,
Ehrt S
,
Schnappinger D
,
Roberts DM
,
Parish T
. 2018.
Identification of Enolase as the Target of 2-Aminothiazoles in .
.
Front Microbiol. 9:2542.
Nötzel C
,
Poran A
,
Kafsack BFC
. 2018.
Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites.
.
Trends Parasitol. 34(9):731-734.
Rafiq S
,
Yeku OO
,
Jackson HJ
,
Purdon TJ
,
van Leeuwen DG
,
Drakes DJ
,
Song M
,
Miele MM
,
Li Z
,
Wang P
et al.
. 2018.
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
.
Nat Biotechnol. 36(9):847-856.
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
2019
Quezada LLopez
,
Silve S
,
Kelinske M
,
Liba A
,
Gonzalez CDiaz
,
Kotev M
,
Goullieux L
,
Sans S
,
Roubert C
,
Lagrange S
et al.
. 2019.
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
.
mBio. 10(4)
Ringe RP
,
Pugach P
,
Cottrell CA
,
LaBranche CC
,
Seabright GE
,
Ketas TJ
,
Ozorowski G
,
Kumar S
,
Schorcht A
,
van Gils MJ
et al.
. 2019.
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.
.
J Virol. 93(4)
Wu J
,
Mu R
,
Sun M
,
Zhao N
,
Pan M
,
Li H
,
Dong Y
,
Sun Z
,
Bai J
,
Hu M
et al.
. 2019.
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .
.
ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Wang C
,
Li Y
,
Chu C-M
,
Zhang X-M
,
Ma J
,
Huang H
,
Wang Y-N
,
Hong T-Y
,
Zhang J
,
Pan X-W
et al.
. 2019.
Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.
.
EBioMedicine. 39:255-264.
Early J
,
Ollinger J
,
Darby C
,
Alling T
,
Mullen S
,
Casey A
,
Gold B
,
Ochoada J
,
Wiernicki T
,
Masquelin T
et al.
. 2019.
Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.
.
ACS Infect Dis. 5(2):272-280.
Wei F
,
Jiang Z
,
Sun H
,
Pu J
,
Sun Y
,
Wang M
,
Tong Q
,
Bi Y
,
Ma X
,
Gao GFu
et al.
. 2019.
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
.
PLoS Pathog. 15(10):e1008062.
Nathan CF
,
Nussenzweig MC
,
Pulvirenti T
. 2019.
JEM Editorial Board: Expanding on the basis of cancer.
.
J Exp Med. 216(8):1725.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
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