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2017
Rock JM
,
Hopkins FF
,
Chavez A
,
Diallo M
,
Chase MR
,
Gerrick ER
,
Pritchard JR
,
Church GM
,
Rubin EJ
,
Sassetti CM
et al.
. 2017.
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
.
Nat Microbiol. 2:16274.
Liu F
,
Dawadi S
,
Maize KM
,
Dai R
,
Park SWoong
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2017.
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
.
J Med Chem. 60(13):5507-5520.
Liu F
,
Dawadi S
,
Maize KM
,
Dai R
,
Park SWoong
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2017.
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
.
J Med Chem. 60(13):5507-5520.
Deitsch KW
,
Dzikowski R
. 2017.
Variant Gene Expression and Antigenic Variation by Malaria Parasites.
.
Annu Rev Microbiol. 71:625-641.
Deitsch KW
,
Dzikowski R
. 2017.
Variant Gene Expression and Antigenic Variation by Malaria Parasites.
.
Annu Rev Microbiol. 71:625-641.
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Dey AK
,
Cupo A
,
Ozorowski G
,
Sharma VK
,
Behrens A-J
,
Go EP
,
Ketas TJ
,
Yasmeen A
,
Klasse PJ
,
Sayeed E
et al.
. 2018.
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
.
Biotechnol Bioeng. 115(4):885-899.
Dey AK
,
Cupo A
,
Ozorowski G
,
Sharma VK
,
Behrens A-J
,
Go EP
,
Ketas TJ
,
Yasmeen A
,
Klasse PJ
,
Sayeed E
et al.
. 2018.
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
.
Biotechnol Bioeng. 115(4):885-899.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Rafiq S
,
Yeku OO
,
Jackson HJ
,
Purdon TJ
,
van Leeuwen DG
,
Drakes DJ
,
Song M
,
Miele MM
,
Li Z
,
Wang P
et al.
. 2018.
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
.
Nat Biotechnol. 36(9):847-856.
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
2019
Ban Y
,
Dong W
,
Zhang L
,
Zhou T
,
Altiti AS
,
Ali K
,
Mootoo DR
,
Blaho VA
,
Hla T
,
Ren Y
et al.
. 2019.
Abrogation of Endogenous Glycolipid Antigen Presentation on Myelin-Laden Macrophages by D-Sphingosine Ameliorates the Pathogenesis of Experimental Autoimmune Encephalomyelitis.
.
Front Immunol. 10:404.
Quezada LLopez
,
Silve S
,
Kelinske M
,
Liba A
,
Gonzalez CDiaz
,
Kotev M
,
Goullieux L
,
Sans S
,
Roubert C
,
Lagrange S
et al.
. 2019.
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
.
mBio. 10(4)
Wu J
,
Mu R
,
Sun M
,
Zhao N
,
Pan M
,
Li H
,
Dong Y
,
Sun Z
,
Bai J
,
Hu M
et al.
. 2019.
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .
.
ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
McLean KJarrod
,
Straimer J
,
Hopp CS
,
Vega-Rodriguez J
,
Small-Saunders JL
,
Kanatani S
,
Tripathi A
,
Mlambo G
,
Dumoulin PC
,
Harris CT
et al.
. 2019.
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.
.
Sci Rep. 9(1):13131.
Early J
,
Ollinger J
,
Darby C
,
Alling T
,
Mullen S
,
Casey A
,
Gold B
,
Ochoada J
,
Wiernicki T
,
Masquelin T
et al.
. 2019.
Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.
.
ACS Infect Dis. 5(2):272-280.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
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