Microbiology and Immunology

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Found 161 results
Author Title Type [ Year(Desc)]
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2001
Becker C, Wirtz S, Ma X, Blessing M, Galle PR, Neurath MF.  2001.  Regulation of IL-12 p40 promoter activity in primary human monocytes: roles of NF-kappaB, CCAAT/enhancer-binding protein beta, and PU.1 and identification of a novel repressor element (GA-12) that responds to IL-4 and prostaglandin E(2).. J Immunol. 167(5):2608-18.
Ehrt S, Schnappinger D, Bekiranov S, Drenkow J, Shi S, Gingeras TR, Gaasterland T, Schoolnik G, Nathan C.  2001.  Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase.. J Exp Med. 194(8):1123-40.
2002
Bryk R, Lima CD, Erdjument-Bromage H, Tempst P, Nathan C.  2002.  Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.. Science. 295(5557):1073-7.
Nathan C.  2002.  Points of control in inflammation.. Nature. 420(6917):846-52.
2003
Shi S, Nathan C, Schnappinger D, Drenkow J, Fuortes M, Block E, Ding A, Gingeras TR, Schoolnik G, Akira S et al..  2003.  MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.. J Exp Med. 198(7):987-97.
K Darwin H, Ehrt S, Gutierrez-Ramos J-C, Weich N, Nathan CF.  2003.  The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.. Science. 302(5652):1963-6.
Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, Dolganov G, Efron B, Butcher PD, Nathan C et al..  2003.  Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.. J Exp Med. 198(5):693-704.
2004
Philpott NJ, Nociari M, Elkon KB, Falck-Pedersen E.  2004.  Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway.. Proc Natl Acad Sci U S A. 101(16):6200-5.
Nathan C.  2004.  Antibiotics at the crossroads.. Nature. 431(7011):899-902.
2005
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Shimosato T, Kitazawa H, Katoh S, Tohno M, Iliev ID, Nagasawa C, Kimura T, Kawai Y, Saito T.  2005.  Augmentation of T(H)-1 type response by immunoactive AT oligonucleotide from lactic acid bacteria via Toll-like receptor 9 signaling.. Biochem Biophys Res Commun. 326(4):782-7.
Hisert KB, MacCoss M, Shiloh MU, K Darwin H, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S et al..  2005.  A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.. Mol Microbiol. 56(5):1234-45.
Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E.  2005.  Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation.. J Virol. 79(18):11627-37.
Nathan C, Calingasan N, Nezezon J, Ding A, M Lucia S, La Perle K, Fuortes M, Lin M, Ehrt S, Kwon NSoo et al..  2005.  Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.. J Exp Med. 202(9):1163-9.
Nathan C, Calingasan N, Nezezon J, Ding A, M Lucia S, La Perle K, Fuortes M, Lin M, Ehrt S, Kwon NSoo et al..  2005.  Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.. J Exp Med. 202(9):1163-9.
Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang X-Y.  2005.  Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.. Proc Natl Acad Sci U S A. 102(10):3772-6.
2006
Cohn EF, Nathan C, Radzioch D, Yu H, Xiang Z, Ding A.  2006.  Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli.. J Immunol. 176(2):1185-94.
Vandal OH, Gelb MH, Ehrt S, Nathan CF.  2006.  Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.. Infect Immun. 74(3):1751-6.
Cheng Y-W, Shawber C, Notterman D, Paty P, Barany F.  2006.  Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.. Genome Res. 16(2):282-9.
Nathan C.  2006.  Neutrophils and immunity: challenges and opportunities.. Nat Rev Immunol. 6(3):173-82.
Tsafrir D, Bacolod M, Selvanayagam Z, Tsafrir I, Shia J, Zeng Z, Liu H, Krier C, Stengel RF, Barany F et al..  2006.  Relationship of gene expression and chromosomal abnormalities in colorectal cancer.. Cancer Res. 66(4):2129-37.
2007
Nathan C.  2007.  Aligning pharmaceutical innovation with medical need.. Nat Med. 13(3):304-8.
Park-Min K-H, Serbina NV, Yang W, Ma X, Krystal G, Neel BG, Nutt SL, Hu X, Ivashkiv LB.  2007.  FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.. Immunity. 26(1):67-78.
Park-Min K-H, Serbina NV, Yang W, Ma X, Krystal G, Neel BG, Nutt SL, Hu X, Ivashkiv LB.  2007.  FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.. Immunity. 26(1):67-78.