Microbiology and Immunology

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2019

Quezada LLopez, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K et al.. 2019. Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .. ACS Infect Dis. 5(8):1433-1445.

Zimmerman M, McDonald SL, Ho-Liang H-P, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS et al.. 2019. Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.. J Antibiot (Tokyo). 72(6):469-475.

Shan J, Chouchane A, Mokrab Y, Saad M, Boujassoum S, Sayaman RW, Ziv E, Bouaouina N, Remadi Y, Gabbouj S et al.. 2019. Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications.. Front Oncol. 9:1328.

Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T et al.. 2019. Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.. ACS Infect Dis. 5(2):272-280.

Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong T-T et al.. 2019. Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.. J Med Chem. 62(13):6137-6145.

Wei F, Jiang Z, Sun H, Pu J, Sun Y, Wang M, Tong Q, Bi Y, Ma X, Gao GFu et al.. 2019. Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.. PLoS Pathog. 15(10):e1008062.

Sanchez AM, Garg A, Shuman S, Schwer B. 2019. Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3' processing and transcription termination.. Nucleic Acids Res. 47(16):8452-8469.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Buter J, Cheng T-Y, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN et al.. 2019. Mycobacterium tuberculosis releases an antacid that remodels phagosomes.. Nat Chem Biol. 15(9):889-899.

Buter J, Cheng T-Y, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN et al.. 2019. Mycobacterium tuberculosis releases an antacid that remodels phagosomes.. Nat Chem Biol. 15(9):889-899.

Freire DMendes, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V et al.. 2019. An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.. Mol Cell. 73(6):1282-1291.e8.

Freire DMendes, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V et al.. 2019. An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.. Mol Cell. 73(6):1282-1291.e8.

Freire DMendes, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V et al.. 2019. An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.. Mol Cell. 73(6):1282-1291.e8.

Freire DMendes, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V et al.. 2019. An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.. Mol Cell. 73(6):1282-1291.e8.

Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S et al.. 2019. Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.. Science. 363(6426)

Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S et al.. 2019. Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.. Science. 363(6426)

Yu EYoung, Cheung IY, Feng Y, Rabie MO, Roboz GJ, Guzman ML, Cheung N-KV, Lue NF. 2019. Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma.. Neoplasia. 21(7):689-701.

2018

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M et al.. 2018. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.. Proc Natl Acad Sci U S A. 115(29):E6863-E6870.

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M et al.. 2018. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.. Proc Natl Acad Sci U S A. 115(29):E6863-E6870.

Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens A-J, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E et al.. 2018. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.. Biotechnol Bioeng. 115(4):885-899.

Oh S, Park Y, Engelhart CA, Wallach JB, Schnappinger D, Arora K, Manikkam M, Gac B, Wang H, Murgolo N et al.. 2018. Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.. J Med Chem. 61(22):9952-9965.