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Filters: Author is Park, Sae Woong  [Clear All Filters]
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Tiwari D, Park SWoong, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M, Ho HPin, Engelhart CA et al..  2018.  Targeting protein biotinylation enhances tuberculosis chemotherapy.. Sci Transl Med. 10(438)
Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al..  2015.  Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.
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Liu F, Dawadi S, Maize KM, Dai R, Park SWoong, Schnappinger D, Finzel BC, Aldrich CC.  2017.  Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem. 60(13):5507-5520.
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Small JL, Park SWoong, Kana BD, Ioerger TR, Sacchettini JC, Ehrt S.  2013.  Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis.. mBio. 4(5):e00475-13.
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Shi C, Geders TW, Park SWoong, Wilson DJ, Boshoff HI, Abayomi O, Barry CE, Schnappinger D, Finzel BC, Aldrich CC.  2011.  Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.. J Am Chem Soc. 133(45):18194-201.
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Dai R, Geders TW, Liu F, Park SWoong, Schnappinger D, Aldrich CC, Finzel BC.  2015.  Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.. J Med Chem. 58(13):5208-17.
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Xu W, DeJesus MA, Rücker N, Engelhart CA, Wright MG, Healy C, Lin K, Wang R, Park SWoong, Ioerger TR et al..  2017.  Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.. Antimicrob Agents Chemother. 61(12)
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.