Microbiology and Immunology

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Pardoux C, Ma X, Gobert S, Pellegrini S, Mayeux P, Gay F, Trinchieri G, Chouaib S. 1999. Downregulation of interleukin-12 (IL-12) responsiveness in human T cells by transforming growth factor-beta: relationship with IL-12 signaling.. Blood. 93(5):1448-55.

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Ma X, Neurath M, Gri G, Trinchieri G. 1997. Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promoter.. J Biol Chem. 272(16):10389-95.

Wang IM, Contursi C, Masumi A, Ma X, Trinchieri G, Ozato K. 2000. An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages.. J Immunol. 165(1):271-9.

Ma X, Aste-Amezaga M, Gri G, Gerosa F, Trinchieri G. 1997. Immunomodulatory functions and molecular regulation of IL-12.. Chem Immunol. 68:1-22.

Chehimi J, Starr SE, Frank I, D'Andrea A, Ma X, MacGregor RR, Sennelier J, Trinchieri G. 1994. Impaired interleukin 12 production in human immunodeficiency virus-infected patients.. J Exp Med. 179(4):1361-6.

Moller DR, Wysocka M, Greenlee BM, Ma X, Wahl L, Trinchieri G, Karp CL. 1997. Inhibition of human interleukin-12 production by pentoxifylline.. Immunology. 91(2):197-203.

Moller DR, Wysocka M, Greenlee BM, Ma X, Wahl L, Flockhart DA, Trinchieri G, Karp CL. 1997. Inhibition of IL-12 production by thalidomide.. J Immunol. 159(10):5157-61.

Ma X, Sun J, Papasavvas E, Riemann H, Robertson S, Marshall J, Bailer RT, Moore A, Donnelly RP, Trinchieri G et al.. 2000. Inhibition of IL-12 production in human monocyte-derived macrophages by TNF.. J Immunol. 164(4):1722-9.

D'Andrea A, Aste-Amezaga M, Valiante NM, Ma X, Kubin M, Trinchieri G. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.. J Exp Med. 178(3):1041-8.

Ma X, Chow JM, Gri G, Carra G, Gerosa F, Wolf SF, Dzialo R, Trinchieri G. 1996. The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells.. J Exp Med. 183(1):147-57.

Sartori A, Ma X, Gri G, Showe L, Benjamin D, Trinchieri G. 1997. Interleukin-12: an immunoregulatory cytokine produced by B cells and antigen-presenting cells.. Methods. 11(1):116-27.

Cassatella MA, Meda L, Gasperini S, D'Andrea A, Ma X, Trinchieri G. 1995. Interleukin-12 production by human polymorphonuclear leukocytes.. Eur J Immunol. 25(1):1-5.

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Aste-Amezaga M, Ma X, Sartori A, Trinchieri G. 1998. Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.. J Immunol. 160(12):5936-44.

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Ma X, Gri G, Trinchieri G. 1996. A novel ets-2-related nuclear factor is involved in transcriptional activation of the human interleukin-12 p40 gene promoter in response to interferon-gamma and LPS stimulation of monocytic cells.. Ann N Y Acad Sci. 795:357-60.

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Ma X, Riemann H, Gri G, Trinchieri G. 1998. Positive and negative regulation of interleukin-12 gene expression.. Eur Cytokine Netw. 9(3 Suppl):54-64.

Karp CL, Wysocka M, Ma X, Marovich M, Factor RE, Nutman T, Armant M, Wahl L, Cuomo P, Trinchieri G. 1998. Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance.. Eur J Immunol. 28(10):3128-36.

Ma X, D'Andrea A, Kubin M, Aste-Amezaga M, Sartori A, Monteiro J, Showe L, Wysocka M, Trinchieri G. 1995. Production of interleukin-12.. Res Immunol. 146(7-8):432-8.

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Aste-Amezaga M, Ma X, Trinchieri G. 1996. Regulation by interleukin-10 of Staphylococcus aureus- and lipopolysaccharide-induced interleukin-12 gene expression in human peripheral blood mononuclear cells.. Ann N Y Acad Sci. 795:319-20.

Ma X, Aste-Amezaga M, Trinchieri G. 1996. Regulation of interleukin-12 production.. Ann N Y Acad Sci. 795:13-25.

Ma X, Trinchieri G. 2001. Regulation of interleukin-12 production in antigen-presenting cells.. Adv Immunol. 79:55-92.

Na SY, Kang BY, Chung SW, Han SJ, Ma X, Trinchieri G, Im SY, Lee JW, Kim TS. 1999. Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB.. J Biol Chem. 274(12):7674-80.

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D'Andrea A, Ma X, Aste-Amezaga M, Paganin C, Trinchieri G. 1995. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production.. J Exp Med. 181(2):537-46.

M Cappiello G, Sutterwala FS, Trinchieri G, Mosser DM, Ma X. 2001. Suppression of Il-12 transcription in macrophages following Fc gamma receptor ligation.. J Immunol. 166(7):4498-506.

Gri G, Savio D, Trinchieri G, Ma X. 1998. Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.. J Biol Chem. 273(11):6431-8.

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Coughlin CM, Salhany KE, Gee MS, LaTemple DC, Kotenko S, Ma X, Gri G, Wysocka M, Kim JE, Liu L et al.. 1998. Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis.. Immunity. 9(1):25-34.