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Found 11 results
Author
Title
Type
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Lin, Gang
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2020
Vanheer LN
,
Zhang H
,
Lin G
,
Kafsack BFC
. 2020.
Activity of Epigenetic Inhibitors against Plasmodium falciparum Asexual and Sexual Blood Stages.
.
Antimicrob Agents Chemother. 64(7)
Moallemian R
,
Rehman AUr
,
Zhao N
,
Wang H
,
Chen H
,
Lin G
,
Ma X
,
Yu J
. 2020.
Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.
.
Biochem Pharmacol. 177:113964.
2019
Zhan W
,
Visone J
,
Ouellette T
,
Harris JC
,
Wang R
,
Zhang H
,
Singh PK
,
Ginn J
,
Sukenick G
,
Wong T-T
et al.
. 2019.
Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.
.
J Med Chem. 62(13):6137-6145.
Zhan W
,
Hsu H-C
,
Morgan T
,
Ouellette T
,
Burns-Huang K
,
Hara R
,
Wright AG
,
Imaeda T
,
Okamoto R
,
Sato K
et al.
. 2019.
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
J Med Chem. 62(20):9246-9253.
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
2017
Totaro KA
,
Barthelme D
,
Simpson PT
,
Jiang X
,
Lin G
,
Nathan C
,
Sauer RT
,
Sello JK
. 2017.
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
ACS Infect Dis. 3(2):176-181.
Santos Rde Luna Al
,
Bai L
,
Singh PK
,
Murakami N
,
Fan H
,
Zhan W
,
Zhu Y
,
Jiang X
,
Zhang K
,
Assker JPierre
et al.
. 2017.
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
.
Nat Commun. 8(1):1692.
2016
Karreci ESula
,
Fan H
,
Uehara M
,
Mihali AB
,
Singh PK
,
Kurdi AT
,
Solhjou Z
,
Riella LV
,
Ghobrial I
,
Laragione T
et al.
. 2016.
Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.
.
Proc Natl Acad Sci U S A. 113(52):E8425-E8432.
2015
Vaubourgeix J
,
Lin G
,
Dhar N
,
Chenouard N
,
Jiang X
,
Botella H
,
Lupoli T
,
Mariani O
,
Yang G
,
Ouerfelli O
et al.
. 2015.
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
.
Cell Host Microbe. 17(2):178-90.
2013
Lin G
,
Chidawanyika T
,
Tsu C
,
Warrier T
,
Vaubourgeix J
,
Blackburn C
,
Gigstad K
,
Sintchak M
,
Dick L
,
Nathan C
. 2013.
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
.
J Am Chem Soc. 135(27):9968-71.
2008
Bryk R
,
Gold B
,
Venugopal A
,
Singh J
,
Samy R
,
Pupek K
,
Cao H
,
Popescu C
,
Gurney M
,
Hotha S
et al.
. 2008.
Selective killing of nonreplicating mycobacteria.
.
Cell Host Microbe. 3(3):137-45.