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Found 59 results
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Nathan, Carl F
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2021
Zhang L
,
Jiang X
,
Pfau D
,
Ling Y
,
Nathan CF
. 2021.
Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death.
.
J Exp Med. 218(2)
2019
Quezada LLopez
,
Silve S
,
Kelinske M
,
Liba A
,
Gonzalez CDiaz
,
Kotev M
,
Goullieux L
,
Sans S
,
Roubert C
,
Lagrange S
et al.
. 2019.
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
.
mBio. 10(4)
Wu J
,
Mu R
,
Sun M
,
Zhao N
,
Pan M
,
Li H
,
Dong Y
,
Sun Z
,
Bai J
,
Hu M
et al.
. 2019.
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .
.
ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Early J
,
Ollinger J
,
Darby C
,
Alling T
,
Mullen S
,
Casey A
,
Gold B
,
Ochoada J
,
Wiernicki T
,
Masquelin T
et al.
. 2019.
Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.
.
ACS Infect Dis. 5(2):272-280.
Nathan CF
,
Nussenzweig MC
,
Pulvirenti T
. 2019.
JEM Editorial Board: Expanding on the basis of cancer.
.
J Exp Med. 216(8):1725.
Zhan W
,
Hsu H-C
,
Morgan T
,
Ouellette T
,
Burns-Huang K
,
Hara R
,
Wright AG
,
Imaeda T
,
Okamoto R
,
Sato K
et al.
. 2019.
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
J Med Chem. 62(20):9246-9253.
Mosior J
,
Bourland R
,
Soma S
,
Nathan C
,
Sacchettini J
. 2019.
Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.
.
Protein Sci.
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Yu H
,
Lupoli TJ
,
Kovach A
,
Meng X
,
Zhao G
,
Nathan CF
,
Li H
. 2018.
ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.
.
Proc Natl Acad Sci U S A. 115(41):E9560-E9569.
McAulay K
,
Saito K
,
Warrier T
,
Walsh KFrances
,
Mathurin LDaniel
,
Royal-Mardi G
,
Lee MHee
,
Ocheretina O
,
Pape JWilliam
,
Fitzgerald DW
et al.
. 2018.
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
.
mBio. 9(6)
Mundhra S
,
Bryk R
,
Hawryluk N
,
Zhang T
,
Jiang X
,
Nathan C
. 2018.
Evidence for dispensability of protein kinase R in host control of tuberculosis.
.
Eur J Immunol. 48(4):612-620.
Negri A
,
Javidnia P
,
Mu R
,
Zhang X
,
Vendome J
,
Gold B
,
Roberts J
,
Barman D
,
Ioerger T
,
Sacchettini JC
et al.
. 2018.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
.
ACS Infect Dis. 4(5):771-787.
2017
Botella H
,
Yang G
,
Ouerfelli O
,
Ehrt S
,
Nathan CF
,
Vaubourgeix J
. 2017.
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.
.
mBio. 8(5)
Nathan C
. 2017.
Introduction of Laurie H. Glimcher, MD.
.
J Clin Invest. 127(10):3575.
Nathan C
,
Nussenzweig MC
,
Pulvirenti T
. 2017.
JEM Advisory Editorial Board: Increasing diversity.
.
J Exp Med.
Nathan C
. 2017.
Kunkel Lecture: Fundamental immunodeficiency and its correction.
.
J Exp Med. 214(8):2175-2191.
Nathan C
,
Nussenzweig M
,
Pulvirenti T
. 2017.
The new face of JEM.
.
J Exp Med. 214(12):3467.
Totaro KA
,
Barthelme D
,
Simpson PT
,
Jiang X
,
Lin G
,
Nathan C
,
Sauer RT
,
Sello JK
. 2017.
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
ACS Infect Dis. 3(2):176-181.
Saito K
,
Warrier T
,
Somersan-Karakaya S
,
Kaminski L
,
Mi J
,
Jiang X
,
Park S
,
Shigyo K
,
Gold B
,
Roberts J
et al.
. 2017.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
.
Proc Natl Acad Sci U S A. 114(24):E4832-E4840.
Santos Rde Luna Al
,
Bai L
,
Singh PK
,
Murakami N
,
Fan H
,
Zhan W
,
Zhu Y
,
Jiang X
,
Zhang K
,
Assker JPierre
et al.
. 2017.
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
.
Nat Commun. 8(1):1692.
Gold B
,
Nathan C
. 2017.
Targeting Phenotypically Tolerant Mycobacterium tuberculosis.
.
Microbiol Spectr. 5(1)
2016
Karreci ESula
,
Fan H
,
Uehara M
,
Mihali AB
,
Singh PK
,
Kurdi AT
,
Solhjou Z
,
Riella LV
,
Ghobrial I
,
Laragione T
et al.
. 2016.
Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.
.
Proc Natl Acad Sci U S A. 113(52):E8425-E8432.
Warrier T
,
Kapilashrami K
,
Argyrou A
,
Ioerger TR
,
Little D
,
Murphy KC
,
Nandakumar M
,
Park S
,
Gold B
,
Mi J
et al.
. 2016.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 113(31):E4523-30.
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