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2016
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
2015
Frykman PK
,
Nordenskjöld A
,
Kawaguchi A
,
Hui TT
,
Granström AL
,
Cheng Z
,
Tang J
,
Underhill DM
,
Iliev ID
,
Funari VA
et al.
. 2015.
Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.
.
PLoS One. 10(4):e0124172.
Brestoff JR
,
Kim BS
,
Saenz SA
,
Stine RR
,
Monticelli LA
,
Sonnenberg GF
,
Thome JJ
,
Farber DL
,
Lutfy K
,
Seale P
et al.
. 2015.
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
.
Nature. 519(7542):242-6.
Murray HW
,
Mitchell-Flack M
,
Taylor GA
,
Ma X
. 2015.
IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver.
.
Exp Parasitol. 157:103-9.
Tang J
,
Iliev ID
,
Brown J
,
Underhill DM
,
Funari VA
. 2015.
Mycobiome: Approaches to analysis of intestinal fungi.
.
J Immunol Methods. 421:112-21.
Bockman MR
,
Kalinda AS
,
Petrelli R
,
De la Mora-Rey T
,
Tiwari D
,
Liu F
,
Dawadi S
,
Nandakumar M
,
Rhee KY
,
Schnappinger D
et al.
. 2015.
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
.
J Med Chem. 58(18):7349-7369.
2014
Osborne LC
,
Monticelli LA
,
Nice TJ
,
Sutherland TE
,
Siracusa MC
,
Hepworth MR
,
Tomov VT
,
Kobuley D
,
Tran SV
,
Bittinger K
et al.
. 2014.
Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
.
Science. 345(6196):578-82.
Osborne LC
,
Monticelli LA
,
Nice TJ
,
Sutherland TE
,
Siracusa MC
,
Hepworth MR
,
Tomov VT
,
Kobuley D
,
Tran SV
,
Bittinger K
et al.
. 2014.
Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
.
Science. 345(6196):578-82.
Sander AF
,
Lavstsen T
,
Rask TS
,
Lisby M
,
Salanti A
,
Fordyce SL
,
Jespersen JS
,
Carter R
,
Deitsch K
,
Theander TG
et al.
. 2014.
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
.
Nucleic Acids Res. 42(4):2270-81.
Puckett S
,
Trujillo C
,
Eoh H
,
Marrero J
,
Spencer J
,
Jackson M
,
Schnappinger D
,
Rhee K
,
Ehrt S
. 2014.
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.
.
PLoS Pathog. 10(5):e1004144.
Torgbor C
,
Awuah P
,
Deitsch K
,
Kalantari P
,
Duca KA
,
Thorley-Lawson DA
. 2014.
A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.
.
PLoS Pathog. 10(5):e1004170.
Torgbor C
,
Awuah P
,
Deitsch K
,
Kalantari P
,
Duca KA
,
Thorley-Lawson DA
. 2014.
A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.
.
PLoS Pathog. 10(5):e1004170.
Danilchanka O
,
Sun J
,
Pavlenok M
,
Maueröder C
,
Speer A
,
Siroy A
,
Marrero J
,
Trujillo C
,
Mayhew DL
,
Doornbos KS
et al.
. 2014.
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.
.
Proc Natl Acad Sci U S A. 111(18):6750-5.
Trujillo C
,
Blumenthal A
,
Marrero J
,
Rhee KY
,
Schnappinger D
,
Ehrt S
. 2014.
Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.
.
mBio. 5(2):e00085.
2013
Shi C
,
Tiwari D
,
Wilson DJ
,
Seiler CL
,
Schnappinger D
,
Aldrich CC
. 2013.
Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation.
.
ACS Med Chem Lett. 4(12)
Marrero J
,
Trujillo C
,
Rhee KY
,
Ehrt S
. 2013.
Glucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice.
.
PLoS Pathog. 9(1):e1003116.
Lin G
,
Chidawanyika T
,
Tsu C
,
Warrier T
,
Vaubourgeix J
,
Blackburn C
,
Gigstad K
,
Sintchak M
,
Dick L
,
Nathan C
. 2013.
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
.
J Am Chem Soc. 135(27):9968-71.
Small JL
,
O'Donoghue AJ
,
Boritsch EC
,
Tsodikov OV
,
Knudsen GM
,
Vandal O
,
Craik CS
,
Ehrt S
. 2013.
Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.
.
J Biol Chem. 288(18):12489-99.
2012
Robertson BD
,
Altmann D
,
Barry C
,
Bishai B
,
Cole S
,
Dick T
,
Duncan K
,
Dye C
,
Ehrt S
,
Esmail H
et al.
. 2012.
Detection and treatment of subclinical tuberculosis.
.
Tuberculosis (Edinb). 92(6):447-52.
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