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Found 108 results
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2025
Kent A, Mon KJoy Yee, Hutchins Z, Putzel G, Zhigarev D, Grier A, Jia B, Kortlever RM, Barbet G, Evan GI et al.
. 2025.
A stromal inflammasome Ras safeguard against Myc-driven lymphomagenesis.
.
Nat Immunol. 26(1):53-67.
Nilson DJ, Schwer B, Almo SC, Shuman S, Ghosh A
. 2025.
Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin.
.
Nucleic Acids Res. 53(14)
Kassegne K, Shen H-M, Chen S-B, Xu S-J, Li J, Xu B, Deitsch KW, Wang Y, Zhou X-N, Chen J-H
. 2025.
A subset of Plasmodium falciparum RIFINs is linked to severe malaria risk reduction and engages LILRB1 through a conserved structural motif.
.
EBioMedicine. 122:106041.
Krieger IV, Sukheja P, Yang B, Tang S, Selle D, Woods A, Engelhart C, Kumar P, Harbut MB, Liu D et al.
. 2025.
SuFEx-based antitubercular compound irreversibly inhibits Pks13.
.
Nature.
2026
Hadjimichael E, Deitsch KW
. 2026.
Shifting metabolism alters rRNA expression in malaria parasites.
.
Trends Parasitol.
Prajapati SK, Dong JX, Morahan BJ, Dotrang T, Barbeau MC, Williams AE, Hupalo D, Wilkerson MD, Dalgard CL, Kafsack BFC et al.
. 2026.
A single valine to leucine switch disrupts Plasmodium falciparum AP2-G DNA binding and reveals GDV1's role in ap2-g activation.
.
Nat Commun.
Courbon GM, Makarov V, Cole ST, Schnapinger D, Ehrt S, Rubinstein JL
. 2026.
Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria.
.
EMBO J. 45(8):2785-2807.
Khonde LPeguy, Peton N, Masike K, Valentine T, Zindo F, Fienberg S, Omollo C, Njoroge M, Vallini F, Tammaro C et al.
. 2026.
Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors.
.
Eur J Med Chem. 312:118841.
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