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Found 108 results
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2019
Mosior J, Bourland R, Soma S, Nathan C, Sacchettini J.  2019.  Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.. Protein Sci.
2020
Ruiz C, Huang J, Giardina SF, Feinberg PB, Mirza AH, Bacolod MD, Soper SA, Barany F.  2020.  Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay.. Hum Mutat. 41(5):1051-1068.
Yu EYoung, Zahid SS, Ganduri S, Sutherland JH, Hsu M, Holloman WK, Lue NF.  2020.  Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection.. Commun Biol. 3(1):777.
2021
Moore JP, Offit PA.  2021.  SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants.. JAMA. 325(9):821-822.
Jurgens EMatthew, Ketas TJoseph, Zhao Z, Satlin MJoseph, Small CButkus, Sukhu A, Francomano E, Klasse PJohan, Garcia A, Nguyenduy E et al..  2021.  Serologic response to mRNA COVID-19 vaccination in lymphoma patients.. Am J Hematol. 96(11):E410-E413.
Athapattu US, Amarasekara CA, Immel JR, Bloom S, Barany F, Nagel AC, Soper SA.  2021.  Solid-phase XRN1 reactions for RNA cleavage: application in single-molecule sequencing.. Nucleic Acids Res. 49(7):e41.
Ray PC, Huggett M, Turner PA, Taylor M, Cleghorn LAT, Early J, Kumar A, Bonnett SA, Flint L, Joerss D et al..  2021.  Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth.. ACS Omega. 6(3):2284-2311.
Benjamin B, Sanchez AM, Garg A, Schwer B, Shuman S.  2021.  Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22.. PLoS Genet. 17(3):e1009452.
Calderón F, Fairlamb AH, Strange M, Williams P, Nathan CF.  2021.  Surmounting structural barriers to tackle endemic infectious diseases.. J Exp Med. 218(9)
2022
Malave-Ramos DR, Kennedy K, Key MN, Dou Z, Kafsack BFC.  2022.  Safe, Effective, and Inexpensive Clearance of Mycoplasma Contamination from Cultures of Apicomplexan Parasites with Sparfloxacin.. Microbiol Spectr. 10(5):e0349722.
Laurent P, Yang C, Rendeiro AF, Nilsson-Payant BE, Carrau L, Chandar V, Bram Y, tenOever BR, Elemento O, Ivashkiv LB et al..  2022.  Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.. Sci Immunol. 7(75):eadd4906.
Florini F, Visone JE, Deitsch KW.  2022.  Shared Mechanisms for Mutually Exclusive Expression and Antigenic Variation by Protozoan Parasites.. Front Cell Dev Biol. 10:852239.
Govender P, Müller R, Singh K, Reddy V, Eyermann CJ, Fienberg S, Ghorpade SR, Koekemoer L, Myrick A, Schnappinger D et al..  2022.  Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.. J Med Chem. 65(9):6903-6925.
Hodge EA, Naika GS, Kephart SM, Nguyen A, Zhu R, Benhaim MA, Guo W, Moore JP, Hu S-L, Sanders RW et al..  2022.  Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env.. iScience. 25(6):104449.
Benjamin B, Goldgur Y, Jork N, Jessen HJ, Schwer B, Shuman S.  2022.  Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.. mBio. 13(6):e0308722.
2023
Harris CT, Tong X, Campelo R, Marreiros IM, Vanheer LN, Nahiyaan N, Zuzarte-Luís VA, Deitsch KW, Mota MM, Rhee KY et al..  2023.  Sexual differentiation in human malaria parasites is regulated by competition between phospholipid metabolism and histone methylation.. Nat Microbiol. 8(7):1280-1292.
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H.  2023.  Structure of the human UBR5 E3 ubiquitin ligase.. Structure. 31(5):541-552.e4.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Hsu H-C, Li D, Zhan W, Ye J, Liu YJing, Leung A, Qin J, Crespo B, Gamo F-J, Zhang H et al..  2023.  Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.. Nat Commun. 14(1):8302.
Xu Y, Ehrt S, Schnappinger D, Beites T.  2023.  Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation.. mBio. 14(6):e0104523.
2024
Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ et al..  2024.  Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.. Cell Chem Biol. 31(4):729-742.e13.
Samuel H, Morillo RCampelo, Kafsack BFC.  2024.  Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria Parasites.. Pathogens. 13(11)
Schwer B, Innokentev A, Sanchez AM, Garg A, Shuman S.  2024.  Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.. mBio. 15(7):e0125224.
2025
Florini F, Visone JE, Hadjimichael E, Malpotra S, Nötzel C, Kafsack BFC, Deitsch KW.  2025.  scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance.. Nat Microbiol. 10(6):1417-1430.
Stephanou A, Mantri M, Shankaranarayanan D, Li C, Lagman M, Xiang J, Pan C, Sun Y, Muthukumar T, Machaca K et al..  2025.  Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers.. bioRxiv.