Microbiology and Immunology

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Found 22 results
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2025
Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al..  2025.  The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.
2024
Ahmed A, Joseph AM, Zhou J, Horn V, Uddin J, Lyu M, Goc J, Sockolow RE, Wing JB, Vivier E et al..  2024.  CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation.. Nature. 630(8018):976-983.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
2023
Kengne-Ouafo JA, Bah SY, Kemp A, Stewart L, Amenga-Etego L, Deitsch KW, Rayner JC, Billker O, Binka FN, Sutherland CJ et al..  2023.  The global transcriptome of Plasmodium falciparum mid-stage gametocytes (stages II-IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates.. Microbiol Spectr. 11(5):e0382022.
2022
Green SR, Davis SH, Damerow S, Engelhart CA, Mathieson M, Baragaña B, Robinson DA, Tamjar J, Dawson A, Tamaki FK et al..  2022.  Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.. Nat Commun. 13(1):5992.
2021
Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu X-J, Cooper CB, Dartois V et al..  2021.  The Tuberculosis Drug Accelerator at year 10: what have we learned? Nat Med. 27(8):1333-1337.
2016
Karreci ESula, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T et al..  2016.  Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.. Proc Natl Acad Sci U S A. 113(52):E8425-E8432.
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Resto YAlemán, Alsibaee A, Alzualde A et al..  2016.  Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.. PLoS Pathog. 12(7):e1005763.
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Resto YAlemán, Alsibaee A, Alzualde A et al..  2016.  Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.. PLoS Pathog. 12(7):e1005763.
2015
Frykman PK, Nordenskjöld A, Kawaguchi A, Hui TT, Granström AL, Cheng Z, Tang J, Underhill DM, Iliev ID, Funari VA et al..  2015.  Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.. PLoS One. 10(4):e0124172.
Ukaegbu UE, Deitsch KW.  2015.  The Emerging Role for RNA Polymerase II in Regulating Virulence Gene Expression in Malaria Parasites.. PLoS Pathog. 11(7):e1004926.
Tang J, Iliev ID, Brown J, Underhill DM, Funari VA.  2015.  Mycobiome: Approaches to analysis of intestinal fungi.. J Immunol Methods. 421:112-21.
Müller S, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY.  2015.  Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology.. Cell Host Microbe. 18(5):604-12.
Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O et al..  2015.  Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.. Cell Host Microbe. 17(2):178-90.
Ukaegbu UE, Zhang X, Heinberg AR, Wele M, Chen Q, Deitsch KW.  2015.  A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.. PLoS Genet. 11(5):e1005234.
2014
Underhill DM, Iliev ID.  2014.  The mycobiota: interactions between commensal fungi and the host immune system.. Nat Rev Immunol. 14(6):405-16.
Ukaegbu UE, Kishore SP, Kwiatkowski DL, Pandarinath C, Dahan-Pasternak N, Dzikowski R, Deitsch K.  2014.  Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.. PLoS Pathog. 10(1):e1003854.
2013
Iliev ID, Underhill DM.  2013.  Striking a balance: fungal commensalism versus pathogenesis.. Curr Opin Microbiol. 16(3):366-73.
2012
Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M et al..  2012.  Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis.. Science. 336(6086):1314-7.
2010
Saenz SA, Siracusa MC, Perrigoue JG, Spencer SP, Urban JF, Tocker JE, Budelsky AL, Kleinschek MA, Kastelein RA, Kambayashi T et al..  2010.  IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses.. Nature. 464(7293):1362-6.
2000
Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW et al..  2000.  Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.. Mol Cell. 6(4):861-71.
1996
Onel K, Koff A, Bennett RL, Unrau P, Holloman WK.  1996.  The REC1 gene of Ustilago maydis, which encodes a 3'-->5' exonuclease, couples DNA repair and completion of DNA synthesis to a mitotic checkpoint.. Genetics. 143(1):165-74.