Microbiology and Immunology

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2000
Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  2000.  Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.. Nat Struct Biol. 7(3):215-9.
Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  2000.  Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.. Nat Struct Biol. 7(3):215-9.
1999
Niederweis M, Ehrt S, Heinz C, Klöcker U, Karosi S, Swiderek KM, Riley LW, Benz R.  1999.  Cloning of the mspA gene encoding a porin from Mycobacterium smegmatis.. Mol Microbiol. 33(5):933-45.
Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W.  1999.  Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. J Mol Biol. 285(2):455-61.
Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W.  1999.  Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. J Mol Biol. 285(2):455-61.
Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W.  1999.  Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. J Mol Biol. 285(2):455-61.
Baron U, Schnappinger D, Helbl V, Gossen M, Hillen W, Bujard H.  1999.  Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.. Proc Natl Acad Sci U S A. 96(3):1013-8.
Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J et al..  1999.  Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.. Am J Respir Cell Mol Biol. 20(3):361-70.
Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J et al..  1999.  Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.. Am J Respir Cell Mol Biol. 20(3):361-70.
Ruan J, St John G, Ehrt S, Riley L, Nathan C.  1999.  noxR3, a novel gene from Mycobacterium tuberculosis, protects Salmonella typhimurium from nitrosative and oxidative stress.. Infect Immun. 67(7):3276-83.
Schnappinger D, Schubert P, Berens C, Pfleiderer K, Hillen W.  1999.  Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.. J Biol Chem. 274(10):6405-10.
Schnappinger D, Schubert P, Berens C, Pfleiderer K, Hillen W.  1999.  Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.. J Biol Chem. 274(10):6405-10.
1998
Orth P, Cordes F, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  1998.  Conformational changes of the Tet repressor induced by tetracycline trapping.. J Mol Biol. 279(2):439-47.
Orth P, Cordes F, Schnappinger D, Hillen W, Saenger W, Hinrichs W.  1998.  Conformational changes of the Tet repressor induced by tetracycline trapping.. J Mol Biol. 279(2):439-47.
Orth P, Alings C, Schnappinger D, Saenger W, Hinrichs W.  1998.  Crystallization and preliminary X-ray analysis of the Tet-repressor/operator complex.. Acta Crystallogr D Biol Crystallogr. 54(Pt 1):99-100.
Orth P, Alings C, Schnappinger D, Saenger W, Hinrichs W.  1998.  Crystallization and preliminary X-ray analysis of the Tet-repressor/operator complex.. Acta Crystallogr D Biol Crystallogr. 54(Pt 1):99-100.
Schnappinger D, Schubert P, Pfleiderer K, Hillen W.  1998.  Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.. EMBO J. 17(2):535-43.
Schnappinger D, Schubert P, Pfleiderer K, Hillen W.  1998.  Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.. EMBO J. 17(2):535-43.
Aste-Amezaga M, Ma X, Sartori A, Trinchieri G.  1998.  Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.. J Immunol. 160(12):5936-44.
Gri G, Savio D, Trinchieri G, Ma X.  1998.  Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.. J Biol Chem. 273(11):6431-8.
Coughlin CM, Salhany KE, Gee MS, LaTemple DC, Kotenko S, Ma X, Gri G, Wysocka M, Kim JE, Liu L et al..  1998.  Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis.. Immunity. 9(1):25-34.
1997
Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E et al..  1997.  Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype.. Hum Gene Ther. 8(1):99-109.
Schirmer F, Ehrt S, Hillen W.  1997.  Expression, inducer spectrum, domain structure, and function of MopR, the regulator of phenol degradation in Acinetobacter calcoaceticus NCIB8250.. J Bacteriol. 179(4):1329-36.
MacMicking JD, North RJ, LaCourse R, Mudgett JS, Shah SK, Nathan C.  1997.  Identification of nitric oxide synthase as a protective locus against tuberculosis.. Proc Natl Acad Sci U S A. 94(10):5243-8.
Sartori A, Ma X, Gri G, Showe L, Benjamin D, Trinchieri G.  1997.  Interleukin-12: an immunoregulatory cytokine produced by B cells and antigen-presenting cells.. Methods. 11(1):116-27.