Microbiology and Immunology

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Found 77 results

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2009

Kang YKenneth, Andjelic S, Binley JM, Crooks ET, Franti M, Iyer SPrasad N, Donovan GP, Dey AK, Zhu P, Roux KH et al.. 2009. Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1.. Vaccine. 27(37):5120-32.

2010

de Carvalho LPedro S, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee K. 2010. Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.. Chem Biol. 17(4):323-32.

Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K et al.. 2010. Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.. Virology. 401(2):236-47.

Biswas T, Small J, Vandal O, Odaira T, Deng H, Ehrt S, Tsodikov OV. 2010. Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.. Structure. 18(10):1353-63.

2011

Koo M-S, Manca C, Yang G, O'Brien P, Sung N, Tsenova L, Subbian S, Fallows D, Muller G, Ehrt S et al.. 2011. Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.. PLoS One. 6(2):e17091.

Pejchal R, Doores KJ, Walker LM, Khayat R, Huang P-S, Wang S-K, Stanfield RL, Julien J-P, Ramos A, Crispin M et al.. 2011. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.. Science. 334(6059):1097-103.

Pejchal R, Doores KJ, Walker LM, Khayat R, Huang P-S, Wang S-K, Stanfield RL, Julien J-P, Ramos A, Crispin M et al.. 2011. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.. Science. 334(6059):1097-103.

Harris A, Borgnia MJ, Shi D, Bartesaghi A, He H, Pejchal R, Kang YKenneth, Depetris R, Marozsan AJ, Sanders RW et al.. 2011. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.. Proc Natl Acad Sci U S A. 108(28):11440-5.

2012

Abt MC, Osborne LC, Monticelli LA, Doering TA, Alenghat T, Sonnenberg GF, Paley MA, Antenus M, Williams KL, Erikson J et al.. 2012. Commensal bacteria calibrate the activation threshold of innate antiviral immunity.. Immunity. 37(1):158-70.

Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS et al.. 2012. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation.. Nat Med. 18(4):538-46.

Melchers M, Bontjer I, Tong T, P Y Chung N, Klasse PJohan, Eggink D, Montefiori DC, Gentile M, Cerutti A, Olson WC et al.. 2012. Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.. J Virol. 86(5):2488-500.

2013

Kim J-H, O'Brien KM, Sharma R, Boshoff HIM, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC et al.. 2013. A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.. Proc Natl Acad Sci U S A. 110(47):19095-100.

Janovitz T, Klein IA, Oliveira T, Mukherjee P, Nussenzweig MC, Sadelain M, Falck-Pedersen E. 2013. High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration.. J Virol. 87(15):8559-68.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al.. 2013. Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.

Small JL, O'Donoghue AJ, Boritsch EC, Tsodikov OV, Knudsen GM, Vandal O, Craik CS, Ehrt S. 2013. Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.. J Biol Chem. 288(18):12489-99.

Noti M, Wojno EDTait, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA et al.. 2013. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.. Nat Med. 19(8):1005-13.

Siracusa MC, Saenz SA, Wojno EDTait, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM et al.. 2013. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.. Immunity. 39(6):1158-70.

2014

Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R et al.. 2014. A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.. Nature. 507(7491):253-257.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al.. 2014. Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Janovitz T, Oliveira T, Sadelain M, Falck-Pedersen E. 2014. Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing.. J Virol. 88(5):2481-8.

Raju RM, Jedrychowski MP, Wei J-R, Pinkham JT, Park AS, O'Brien K, Rehren G, Schnappinger D, Gygi SP, Rubin EJ. 2014. Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.. PLoS Pathog. 10(3):e1003994.

2015

Schnappinger D, O'Brien KM, Ehrt S. 2015. Construction of conditional knockdown mutants in mycobacteria.. Methods Mol Biol. 1285:151-75.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al.. 2015. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science. 349(6244):aac4223.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al.. 2015. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science. 349(6244):aac4223.

Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW et al.. 2015. Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.. J Virol. 89(23):12189-210.