Microbiology and Immunology

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Found 161 results
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2012
Nathan C.  2012.  Fresh approaches to anti-infective therapies.. Sci Transl Med. 4(140):140sr2.
Wu K, Koo J, Jiang X, Chen R, Cohen SN, Nathan C.  2012.  Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R.. PLoS One. 7(2):e30512.
Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M et al..  2012.  Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis.. Science. 336(6086):1314-7.
Blumenthal A, Nagalingam G, Huch JH, Walker L, Guillemin GJ, Smythe GA, Ehrt S, Britton WJ, Saunders BM.  2012.  M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.. PLoS One. 7(5):e37314.
2011
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Berro R, Klasse PJohan, Lascano D, Flegler A, Nagashima KA, Sanders RW, Sakmar TP, Hope TJ, Moore JP.  2011.  Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.. J Virol. 85(16):8227-40.
Darby CM, Venugopal A, Ehrt S, Nathan CF.  2011.  Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice.. Tuberculosis (Edinb). 91(5):343-7.
de Carvalho LPedro S, Darby CM, Rhee KY, Nathan C.  2011.  Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.. ACS Med Chem Lett. 2(11):849-854.
Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C.  2011.  Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.. Cell Host Microbe. 9(1):21-31.
2010
de Carvalho LPedro S, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee K.  2010.  Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.. Chem Biol. 17(4):323-32.
Yin F, Banerjee R, Thomas B, Zhou P, Qian L, Jia T, Ma X, Ma Y, Iadecola C, M Beal F et al..  2010.  Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice.. J Exp Med. 207(1):117-28.
Beaulieu AM, Rath P, Imhof M, Siddall ME, Roberts J, Schnappinger D, Nathan CF.  2010.  Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.. PLoS One. 5(12):e15120.
Seimon TA, Kim M-J, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker L-G, Kaplan G, Nathan C, Tabas I et al..  2010.  Induction of ER stress in macrophages of tuberculosis granulomas.. PLoS One. 5(9):e12772.
Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K et al..  2010.  Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.. Virology. 401(2):236-47.
de Carvalho LPedro S, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY.  2010.  Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.. Chem Biol. 17(10):1122-31.
Tan MPing, Sequeira P, Lin WWei, Phong WYee, Cliff P, Ng SHwee, Lee BHeng, Camacho L, Schnappinger D, Ehrt S et al..  2010.  Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses.. PLoS One. 5(10):e13356.
Nathan C, Ding A.  2010.  Nonresolving inflammation.. Cell. 140(6):871-82.
Sonnenberg GF, Nair MG, Kirn TJ, Zaph C, Fouser LA, Artis D.  2010.  Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A.. J Exp Med. 207(6):1293-305.
2009
Vandal OH, Nathan CF, Ehrt S.  2009.  Acid resistance in Mycobacterium tuberculosis.. J Bacteriol. 191(15):4714-21.
Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S.  2009.  Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.. J Bacteriol. 191(2):625-31.
Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E.  2009.  Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.. J Virol. 83(9):4081-91.
Noguchi E, Homma Y, Kang X, Netea MG, Ma X.  2009.  A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.. Nat Immunol. 10(5):471-9.
Noguchi E, Homma Y, Kang X, Netea MG, Ma X.  2009.  A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.. Nat Immunol. 10(5):471-9.
Bacolod MD, Schemmann GS, Giardina SF, Paty P, Notterman DA, Barany F.  2009.  Emerging paradigms in cancer genetics: some important findings from high-density single nucleotide polymorphism array studies.. Cancer Res. 69(3):723-7.
Nathan C.  2009.  Taming tuberculosis: a challenge for science and society.. Cell Host Microbe. 5(3):220-4.