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2024
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.
. 2024.
Tuberculosis in otherwise healthy adults with inherited TNF deficiency.
.
Nature. 633(8029):417-425.
Lee AM, Nathan CF
. 2024.
Type I interferon exacerbates Mycobacterium tuberculosis induced human macrophage death.
.
EMBO Rep. 25(7):3064-3089.
Song M, Huang S, Wu X, Zhao Z, Liu X, Wu C, Wang M, Gao J, Ke Z, Ma X et al.
. 2024.
UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling.
.
Redox Biol. 76:103349.
Hahn WO, K Parks R, Shen M, Ozorowski G, Janes H, Ballweber-Fleming L, Davis ASWoodward, Duplessis C, Tomai M, Dey AK et al.
. 2024.
Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies.
.
J Exp Med. 221(10)
Syed S, Aloe S, Sutherland JH, Holloman WK, Lue NF
. 2024.
Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.
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PLoS Genet. 20(12):e1011515.
2023
Colin P, Ringe RP, Yasmeen A, Ozorowski G, Ketas TJ, Lee W-H, Ward AB, Moore JP, Klasse PJ
. 2023.
Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
.
Retrovirology. 20(1):9.
Wong AI, Beites T, Planck KA, Fieweger RA, Eckartt KA, Li S, Poulton NC, VanderVen BC, Rhee KY, Schnappinger D et al.
. 2023.
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis.
.
Elife. 12
Zhan W, Li D, Subramanyaswamy SBevkal, Liu YJing, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H et al.
. 2023.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
.
Cell Chem Biol. 30(5):457-469.e11.
Zhan W, Li D, Subramanyaswamy SBevkal, Liu YJing, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H et al.
. 2023.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
.
Cell Chem Biol. 30(5):457-469.e11.
Zhan W, Li D, Subramanyaswamy SBevkal, Liu YJing, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H et al.
. 2023.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
.
Cell Chem Biol. 30(5):457-469.e11.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al.
. 2023.
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
.
Cell Rep Med. 4(4):101003.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al.
. 2023.
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
.
Cell Rep Med. 4(4):101003.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al.
. 2023.
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
.
Cell Rep Med. 4(4):101003.
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JHyun, Antanasijevic A, Rantalainen K, Ketas T et al.
. 2023.
Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
.
PLoS Pathog. 19(10):e1011601.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al.
. 2023.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.
.
Nat Commun. 14(1):1756.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al.
. 2023.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.
.
Nat Commun. 14(1):1756.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al.
. 2023.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.
.
Nat Commun. 14(1):1756.
Capucci S, Wee EG, Schiffner T, LaBranche CC, Borthwick N, Cupo A, Dodd J, Dean H, Sattentau Q, Montefiori D et al.
. 2023.
HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.
.
PLoS One. 18(10):e0293148.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al.
. 2023.
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.
.
J Med Chem. 66(22):15380-15408.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al.
. 2023.
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.
.
J Med Chem. 66(22):15380-15408.
Sharma I, Fang J, Lewallen EA, Deitsch KW, McCutchan TF
. 2023.
Identification of a long noncoding RNA required for temperature induced expression of stage-specific rRNA in malaria parasites.
.
Gene. 877:147516.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al.
. 2023.
Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.
.
Nucleic Acids Res. 51(2):668-686.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al.
. 2023.
Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.
.
Nucleic Acids Res. 51(2):668-686.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al.
. 2023.
Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.
.
Nucleic Acids Res. 51(2):668-686.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al.
. 2023.
Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.
.
ACS Med Chem Lett. 14(7):970-976.
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